PSI-7976

CAS No.: 1190308-01-0

Chemical Name:: PSI-7976

Synonyms: PSI-7976;SFB-L-ALANITE-MODEL;SFB-L-Alaninate-Model;Sofosbuvir (R)-Phosphate;Sofosbuvir phosphate salt;(R)-(((2R,3R,4R,5R)-L-Sofosbuvir Isomer(Sofosbuvir INT Impurity A);N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate

CBNumber:: CB42685935

Molecular Formula:: C22H29FN3O9P

Molecular Weight:: 529.45

MOL File:: 1190308-01-0.mol

Modify Date:: 2023/5/18 11:31:12

Request For Quotation

PSI-7976 Properties

Melting point	76-82°C
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly)
pka	9.39±0.10(Predicted)
form	Solid
color	White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

PSI-7976 Chemical Properties,Uses,Production

Uses

Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7976 Preparation Products And Raw materials

Raw materials

Preparation Products

PSI-7976 Suppliers

Global( 87)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Varanous Labs Pvt Ltd	+91-7036248882 +91-7036248882	Hyderabad, India	1541	58	Inquiry
SynThink RESEARCH CHEMICALS	+91-8177860948 +91-8177860948	Mumbai, India	494	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
CLEANCHEM LABORATORIES LLP	+91 98921 69560	New Delhi, India	326	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
sgtlifesciences pvt ltd	+8617013299288	China	12382	58	Inquiry
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11927	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry

Supplier	Advantage
Varanous Labs Pvt Ltd	58
SynThink RESEARCH CHEMICALS	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
CLEANCHEM LABORATORIES LLP	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Wuhan Topule Biopharmaceutical Co., Ltd	58

1190308-01-0(PSI-7976)Related Search:

GAMMA-CYHALOTHRIN Sofosbuvir metabolites Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) PSI-7977-13C-d3 Sofosbuvir

SofosBuvir impurity 45 SofosBuvir Impurity 53 sofosBuvir Impurity 37 PSI 7411 Sofosbuvir Impurity 6

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Sofosbuvir Impurity27 SofosBuvir Impurity 38 Sofosbuvir impurity I (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

Sofosbuvir impurity D SofosBuvir Impurity 31 sofosBuvir Impurity 33

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PSI-7976 N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester Sofosbuvir (R)-Phosphate (S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate Sofosbuvir L-alanitate (Mixture of Diasteriomers)Q: What is Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the CAS Number of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the storage condition of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What are the applications of Sofosbuvir L-alanitate (Mixture of Diasteriomers) SFB-L-Alaninate-Model Sofosbuvir phosphate salt Sofosbuvir impurity 14/ RP-Isomer of Sofosbuvir/Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate SFB-L-ALANITE-MODEL (R)-(((2R,3R,4R,5R)-L-Sofosbuvir Isomer(Sofosbuvir INT Impurity A) 1190308-01-0 190308-01-0