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PSI-7977-13C-d3

CAS No.: 2070009-25-3

Chemical Name:: PSI-7977-13C-d3

Synonyms: PSI-7977-13C-d3;[13C,2H3]-Sofosbuvir;L-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-(methyl-13C-d3)-P-phenyl-5′-uridylyl]-, 1-methylethyl ester;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3

CBNumber:: CB64666758

Molecular Formula:: C22H26D3FN3O9P

Molecular Weight:: 533.46

MOL File:: 2070009-25-3.mol

Modify Date:: 2025/1/16 8:02:57

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PSI-7977-13C-d3 Properties

Density	1.413±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp.	Store at -20°C
solubility	DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml
form	A solid

PSI-7977-13C-d3 Chemical Properties,Uses,Production

Description

PSI-7977-¹³C-d₃ is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC₅₀ = 92 nM). PSI-7977 is effective in vitro and in vivo.

Uses

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 Preparation Products And Raw materials

Raw materials

Preparation Products

PSI-7977-13C-d3 Suppliers

Global( 18)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23541	58	Inquiry
Cayman Chemical Company	(800) 364-9897	United States	6213	81	Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	China	12582	58	Inquiry
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	China	11973	58	Inquiry
Cayman Chemical Company	800-364-9897	China	21645	58	Inquiry
Shanghai Moqi Biological Technology Co., LTD	021-38218169 13341702378	China	9910	58	Inquiry
Biosynth Biological Technology (Suzhou) Co Ltd	51288865780	China	233051	58	Inquiry
Hubei Moco Chemical Co., Ltd.	18627756402	China	19217	58	Inquiry
United States Biological	1-800-520-3011	United States	6075	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
ANHUI WITOP BIOTECH CO., LTD	58
Cayman Chemical Company	81
Nanjing Shizhou Biology Technology Co.,Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Cayman Chemical Company	58
Shanghai Moqi Biological Technology Co., LTD	58
Biosynth Biological Technology (Suzhou) Co Ltd	58
Hubei Moco Chemical Co., Ltd.	58
United States Biological	58

2070009-25-3(PSI-7977-13C-d3)Related Search:

Sofosbuvir IMpurity ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-Methyltetrahydrofuran-2-yl)Methyl benzoate Sofosbuvir Impurity 8 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI)

Sofosbuvir alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate Sofosbuvir Impurity 19 PSI 352707-13C,D3 PSI-7976

Sofosbuvir D6 Sofosbuvir Impurity Sofosbuvir metabolites GS566500 Sofosbuvir metabolites PSI 7411

Sofosbuvir Impurity 32 PSI-6206 13CD3 (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

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[13C,2H3]-Sofosbuvir isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3 PSI-7977-13C-d3 L-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-(methyl-13C-d3)-P-phenyl-5′-uridylyl]-, 1-methylethyl ester 2070009-25-3 C2113CH26D3FN3O9P