ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Standard Substance >PSI-7977-13C-d3

PSI-7977-13C-d3

PSI-7977-13C-d3 Structure
CAS No.
2070009-25-3
Chemical Name:
PSI-7977-13C-d3
Synonyms
[13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
CBNumber:
CB64666758
Molecular Formula:
C2113CH26D3FN3O9P
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2023/5/21 10:59:17

PSI-7977-13C-d3 Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml
form A solid

PSI-7977-13C-d3 Chemical Properties,Uses,Production

Description

PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.

Uses

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 Preparation Products And Raw materials

Raw materials

Preparation Products

PSI-7977-13C-d3 Suppliers

Global( 16)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8740 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900 China 12584 58 Inquiry
PureChemland Co.,Ltd. 19150123681 China 3242 58 Inquiry
Hubei Moco Chemical Co., Ltd. 18627753421 17386083646 China 10906 58 Inquiry
United States Biological 1-800-520-3011 United States 6106 58 Inquiry
Medical Isotopes, Inc (603)635-2255 United States 3183 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
[13C,2H3]-Sofosbuvir isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3 2070009-25-3 C2113CH26D3FN3O9P