PSI-7977-13C-d3
- CAS No.
- 2070009-25-3
- Chemical Name:
- PSI-7977-13C-d3
- Synonyms
- [13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
- CBNumber:
- CB64666758
- Molecular Formula:
- C2113CH26D3FN3O9P
- Molecular Weight:
- 0
- MOL File:
- Mol file
- Modify Date:
- 2023/5/21 10:59:17
PSI-7977-13C-d3 Chemical Properties,Uses,Production
Description
PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.
Uses
PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
PSI-7977-13C-d3 Preparation Products And Raw materials
Raw materials
Preparation Products
PSI-7977-13C-d3 Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | China | 8740 | 58 | Inquiry |
Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | China | 12584 | 58 | Inquiry |
PureChemland Co.,Ltd. | 19150123681 | China | 3242 | 58 | Inquiry |
Hubei Moco Chemical Co., Ltd. | 18627753421 17386083646 | China | 10906 | 58 | Inquiry |
United States Biological | 1-800-520-3011 | United States | 6106 | 58 | Inquiry |
Medical Isotopes, Inc | (603)635-2255 | United States | 3183 | 58 | Inquiry |
Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
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