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3,5-Bis(2-cyanoprop-2-yl)toluene

3,5-Bis(2-cyanoprop-2-yl)toluene Structure
CAS No.
120511-72-0
Chemical Name:
3,5-Bis(2-cyanoprop-2-yl)toluene
Synonyms
2-(5-methyl-1;AnastrozoleImp.A;Compound PDK0045;13,αAnastrozole Impurity H;Anastrozole EP Impurity H;Anastrozole EP Impuriyt H;Anastrazole EP Impurity-H;α1,α1,α3,α3,5-PentaMethyl-
CBNumber:
CB4277147
Molecular Formula:
C15H18N2
Molecular Weight:
226.32
MOL File:
120511-72-0.mol
Modify Date:
2023/5/22 12:34:27

3,5-Bis(2-cyanoprop-2-yl)toluene Properties

Melting point 127-130°C
Boiling point 339.1±32.0 °C(Predicted)
Density 1.002±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
color White to Off-White
InChI InChI=1S/C15H18N2/c1-11-6-12(14(2,3)9-16)8-13(7-11)15(4,5)10-17/h6-8H,1-5H3
InChIKey SJECEXNMZXMXNE-UHFFFAOYSA-N
SMILES C1(=CC(C)=CC(C(C)(C)C#N)=C1)C(C)(C)C#N
CAS DataBase Reference 120511-72-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2926900005

3,5-Bis(2-cyanoprop-2-yl)toluene Chemical Properties,Uses,Production

Chemical Properties

3,5-Bis(2-cyanoprop-2-yl)toluene is White Solid

Uses

3,5-Bis(2-cyanoprop-2-yl)toluene is a labelled intermediate in the synthesis of Anastrozole, an aromatase inhibitor. Used as an antineoplastic.

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PENTAMETHYL-1,3-BENZENEDIACETONITRILE 2,2'-(5-METHYL-1,3-PHENYLENE)DI(2-METHYLPROPANENITRILE) 2,2'-(5-methyl-1,3-phenylene)di(2-methylpropionitrile) 3,5-Bis (2-cyanoisopropyl ) toluene 2,2’-(5-Methyl-1,3-phenylene)-di(2-methylpropiononitrile 2,2'-(5-Methyl-1,3-Phenylene)Bis(2-Methylpropanenitrile) 2,2-(5-Methyl-1,3-Phenylene)-Bis-(2-Methyl-Propionitrile) 3,5-Bis(2-Cyanoisopropyl)Toluene(ForAnastrozole) 2,2-(5-methyl-1,3-phenylene)di(2-methylpropiononitrile (intermediate of anastrozole) 5-a,a,a',a'-Pentamethyl-1,3-Benzenediacetonitrile -(5-Methyl-1,3-phenylene)-di(2-methylpropiononitrile A,A,A'',A'',5-PENTAMETHYL1,3 BENZENEDIACETONITRIL 2-[3-(CYANO-DIMETHYL-METHYL)-5-METHYL-PHENYL]-2-METHYLPROPIONITRIL 2,2’-(5-Methyl-m-phenylene)bis-(2-methyl-propionitrile) A,A,A',A',5-PENTAMETHYL-1,3 BENZENEDIACETONITRILE 5-PENTAMETHYL-1,3-BENZENEDIACETONITRILE 3,5-Bis(2-cyanoprop-2-yl)toluene 3,5-DI[(2,2-DIMETHYL)CYANOMETHYL]TOLUENE 2-[3-(Cyanodimethylmethyl)-5-methylphenyl]-2-methylpropionitrile 1,3-Benzenediacetonitrile, α,α,α',α',5-pentamethyl- 3,5-Bis(2-cyanoprop-2-yl)toluene 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropionitrile)a,a,a',a',5-Pentamethyl-1,3-benzenediacetonitrile 3,5-BIS(2-CYANOPROP-2-YL)TOLUENE,98% α,α,α',α',5-pentamethyl-1,3-benzenediacetonitril α,α,α’,α’-Tetramethyl-5-methyl-1,3-benzenediacetonitrile 2-[3-(1-cyano-1-methylethyl)-5-methylphenyl]-2-methylpropanenitrile Anastrozole Related Compound A (20 mg) (2,2'-(5-methyl-1,3-phenylene)bis(2-methylpropanenitrile)) 2-[2-(1-cyano-1-Methylethyl)-5-Methylphenyl]-2-Methylpropanenitrile α1,α1,α3,α3,5-PentaMethyl- α,α,α',α'-TetraMethyl-5-Methyl-1,3-benzenediacetonitrile-d12 Anastrozole Related CoMpound A 1,3-Benzenediacetonitrile,a1,a1,a3,a3,5-pentaMethyl- 2,2'-(5-Methyl-1,3-phenylene)di(2-Methylpropionoitrile) 2,2,2'2'-(5-Methyl-1,3-phenylene)-dimethyl-propionitrile Anastrozole EP Impurity H 1,&alpha 3,&alpha 3,5-pentaMethyl- 1,3-Benzenediacetonitrile, &alpha 2-(5-methyl-1 3-phenylene)-bis-(2-methyl-propionitrile) Anastrozole USP Related Compound A Anastrozole EP Impuriyt H Anastrozole Impurity 13(EP Impurity H) 2,2'-(5-methylbenzene-1,3-diyl)bis(2-methylpropanenitrile) 2-[3-(1-cyanoethyl)-5-methylphenyl]-2-methylpropanenitrile 2,2'-(5-Methylbenzene-1,3-diyl)bis( 1,3-Benzenediacetonitrile, α1,α1,α3,α3,5-pentamethyl- 2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile 3,5-Bis(2-cyanoprop-2-yl)toluene(For export only) 3,5-Bis(2-cyanoprop-2-yl)toluene ISO 9001:2015 REACH Anastrozole Impurity 13(Anastrozole EP Impurity H) 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropionitrile) for anastrozole 2,2'-(5-Methyl-1,3-phenylene)bis Anastrozole EP Impurity H/ Anastrozole Related Compound A Anastrozole EP Impurity HQ: What is Anastrozole EP Impurity H Q: What is the CAS Number of Anastrozole EP Impurity H Q: What is the storage condition of Anastrozole EP Impurity H Q: What are the applications of Anastrozole EP Impurity H Anastrozole Related Compound A (2,2''-(5-methyl-1,3-phenylene)bis(2-methylpropanenitrile)) (1034818) α,α,α'',α''-Tetramethyl-5-methyl-1,3-benzenediacetonitrile Anastrozole Impurity H