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2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE Structure
CAS No.
76081-98-6
Chemical Name:
2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE
Synonyms
S28080;SCH 28080;SCH-28080,SCH28080;SCH28080, 10 mM in DMSO;Schering compound 28080;imidazo-(1-2-a)pyrine-3-acetonitrile;2-Methyl-8-(phenylmethoxy)imidazo-(1-2-A)pyrine-3-acetonitrile;2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE;2-(8-(Benzyloxy)-2-methylimidazo[1,2-a]pyridin-3-yl)acetonitrile;Imidazo(1,2-A)pyridine-3-acetonitrile, 2-methyl-8-(phenylmethoxy)-
CBNumber:
CB4281209
Molecular Formula:
C17H15N3O
Molecular Weight:
277.32
MOL File:
76081-98-6.mol
MSDS File:
SDS
Modify Date:
2025/1/27 9:38:02
Request For Quotation

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE Properties

Density 1.16±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: >10 mg/mL, soluble
form solid
pka 5.85±0.10(Predicted)
color white to light tan

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S4443 SCH-28080 ≥98% (HPLC), solid 76081-98-6 10MG ₹21141.23 2022-06-14 Buy
Sigma-Aldrich(India) S4443 SCH-28080 ≥98% (HPLC), solid 76081-98-6 50MG ₹93733.68 2022-06-14 Buy
Product number Packaging Price Buy
S4443 10MG ₹21141.23 Buy
S4443 50MG ₹93733.68 Buy

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE Chemical Properties,Uses,Production

Description

SCH 28080 is a reversible K+-competitive inhibitor of H+/K+-ATPases that is best known for its ability to block acid secretion through its action against the gastric H+/K+-ATPase (IC50 = 1.3 μM). It is effective against gastric H+/K+-ATPases from a variety of species and can inhibit colonic H+/K+-ATPases, but this activity appears to be species-dependent. SCH 28080 is also used to investigate the role of H+/K+-ATPases in non-mammalian organisms and to distinguish the actions of H+/K+-ATPases from other ATP-dependent transporters.

Uses

SCH 28080 is a potent inhibitor of H+,K+-ATPase.

Biological Activity

Potent inhibitor of H + ,K + -ATPase (IC 50 = 20 nM); binds to the K + recognition site and is competitive with respect to K + . Inhibits gastric acid secretion in vitro and in vivo .

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE Suppliers

Global( 69)Suppliers
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TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32239 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8467 58 Inquiry
Aladdin Scientific United States 57505 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. 400-6206333 13167063860 China 48458 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9835 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24739 58 Inquiry
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4613 55 Inquiry
Bide Pharmatech Ltd. 400-1647117 13681763483 China 62072 58 Inquiry
Biorbyt Ltd. +44 (0)1223 859 353 CHINA 6482 58 Inquiry
Proteintech China 027-87531629 CHINA 6290 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Bide Pharmatech Ltd. 58
Biorbyt Ltd. 58
Proteintech China 58

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE Spectrum

2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE(76081-98-6)1HNMR

76081-98-6(2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE)Related Search:

4(5)-CYANOMETHYLIMIDAZOLE 2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE (1,4-DIMETHYL-1H-IMIDAZOL-2-YL)METHANOL 2-Methylimidazo[1,2-a]pyridin-8-ol 8-BENZYLOXY-IMIDAZO[1,2-A]PYRIDINE
3-Cyanomethyl-2-methylimidazo(1,2-a)pyridine (1-Methyl-1H-imidazol-2-yl)methanol Imidazo[1,2-a]pyridin-8-ol (9CI) IMIDAZO[1,2-A]PYRIDIN-3-YL-ACETONITRILE
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3-(CYANOMETHYL)-2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-ALPHA]PYRIDINE 2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-A]PYRIDINE-3-ACETONITRILE 2-Methyl-8-(phenylmethoxy)imidazo-(1-2-A)pyrine-3-acetonitrile Imidazo(1,2-A)pyridine-3-acetonitrile, 2-methyl-8-(phenylmethoxy)- S28080 Schering compound 28080 SCH 28080 imidazo-(1-2-a)pyrine-3-acetonitrile SCH-28080,SCH28080 2-(8-(Benzyloxy)-2-methylimidazo[1,2-a]pyridin-3-yl)acetonitrile SCH28080, 10 mM in DMSO 76081-98-6 Ion Pump Inhibitors Ion Channels Monovalent Ion Channels Voltage-gated Ion Channels BioChemical Cell Signaling and Neuroscience Cell Biology ATPase