JNJ 63533054
- CAS No.
- 1802326-66-4
- Chemical Name:
- JNJ 63533054
- Synonyms
- CS-2223;JNJ 63533054;JNJ-63533054 (JNJ63533054;JNJ-63533054 >=98% (HPLC);(S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl)benzamide;3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide;Benzamide, 3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]-;L-tryptophan,blood-brain,oral,CNS,L-phenylalanine,G Protein-Coupled Receptor 139,barrier,JNJ63533054,Inhibitor,GPR139,JNJ-63533054,inhibit
- CBNumber:
- CB43110757
- Molecular Formula:
- C17H17ClN2O2
- Molecular Weight:
- 316.78
- MOL File:
- 1802326-66-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/7/14 17:44:29
| Boiling point | 559.7±45.0 °C(Predicted) |
|---|---|
| Density | 1.224±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | Soluble in DMSO (up to 35 mg/ml). |
| pka | 12.77±0.46(Predicted) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D -89 to -99°, c = 1 in ethanol |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| NFPA 704 |
|
JNJ 63533054 price More Price(2)
JNJ 63533054 Chemical Properties,Uses,Production
Uses
JNJ 63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
Biochem/physiol Actions
JNJ-63533054 is a potent and selective agonist of the orphan receptor hGPR139, a GPCR receptor expressed in the brain in circumventricular regions of the habenula and septum. JNJ-63533054 has an EC50 value of 16 nM, crosses the blood-brain barrier, and is orally available.
JNJ 63533054 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 64)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | China | 694 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
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JNJ 63533054
3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
CS-2223
JNJ-63533054 (JNJ63533054
Benzamide, 3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]-
JNJ-63533054 >=98% (HPLC)
(S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl)benzamide
L-tryptophan,blood-brain,oral,CNS,L-phenylalanine,G Protein-Coupled Receptor 139,barrier,JNJ63533054,Inhibitor,GPR139,JNJ-63533054,inhibit
1802326-66-4