ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Esters >Ethyl compound >Ethyl 2-chloronicotinate
Ethyl 2-chloronicotinate
- CAS No.
- 1452-94-4
- Chemical Name:
- Ethyl 2-chloronicotinate
- Synonyms
- AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;ETHYL 2-CHLORONICOTINATE;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C;Ethyl2-chloronicotinate,98%;Flunixin Meglumine Impurity C
- CBNumber:
- CB4312224
- Molecular Formula:
- C8H8ClNO2
- Molecular Weight:
- 185.61
- MOL File:
- 1452-94-4.mol
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | 68 C |
|---|---|
| Boiling point | 78°C (0.1 mmHg) |
| Density | 1.2445 g/cm3(Temp: 25 °C) |
| refractive index | 1.5210-1.5250 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -1.32±0.10(Predicted) |
| form | Liquid |
| color | Colorless to Light yellow to Light orange |
| InChI | InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3 |
| InChIKey | PMIMPBYTPPRBGD-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=CC=C1C(OCC)=O |
| CAS DataBase Reference | 1452-94-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-60-37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
Ethyl 2-chloronicotinate price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR2413 | Flunixin Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material | 1452-94-4 | 50MG | ₹45529.95 | 2022-06-14 | Buy |
| TCI Chemicals (India) | E0844 | Ethyl 2-Chloronicotinate min. 98.0 % | 1452-94-4 | 25G | ₹6200 | 2022-05-26 | Buy |
| ALFA India | ALF-B20359-30 | Ethyl 2-chloronicotinate, 98% | 1452-94-4 | 250g | ₹25872 | 2022-05-26 | Buy |
| ALFA India | ALF-B20359-18 | Ethyl 2-chloronicotinate, 98% | 1452-94-4 | 50g | ₹6436 | 2022-05-26 | Buy |
| TCI Chemicals (India) | E0844 | Ethyl 2-Chloronicotinate min. 98.0 % | 1452-94-4 | 100G | ₹14800 | 2022-05-26 | Buy |
Ethyl 2-chloronicotinate Chemical Properties,Uses,Production
Chemical Properties
Light yellow liquid
Uses
Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.
Synthesis Reference(s)
Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A
Synthesis
2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.
Ethyl 2-chloronicotinate Preparation Products And Raw materials
Global( 308)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Sadasivarao g | +91 9515157878 | Hyderabad, India | 107 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Sadasivarao g | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Alfa Aesar | 58 |
| SynZeal Research Pvt Ltd | 58 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
| Pharma Affiliates | 58 |
| Clearsynth Labs | 58 |
| Vyas Bio Life Sciences Pvt. Ltd | 58 |
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Flunixin Related CoMpound C
Ethyl 2-chloronicotinate, 99%, 99%
Ethyl2-chloronicotinate,98%
AVAC-001
oronicotinate
Flunixin Meglumine Impurity 3（Flunixin Meglumine EP Impurity C）
Flunixin Meglumine EP Impurity C
Ethyl2-Chloronicotinate>
Ethyl 2-Chloropyridine-3-carboxylat
Flunixin EP Impurity C
Flunixin impurity CQ: What is
Flunixin impurity C Q: What is the CAS Number of
Flunixin impurity C Q: What is the storage condition of
Flunixin impurity C Q: What are the applications of
Flunixin impurity C
Flunixin Related Compound C (Ethyl 2-chloronicotinate) (1274631)
Flunixin USP Related Compound C
ethy-2-chloroisonicoitate
Flunixin Meglumine Impurity C
1452-94-4
C8HBCINO2
pyridine series
Pyridines
Pharmaceutical Intermediates
Pyridine
Fluorobenzene