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ChemicalBook > Product Catalog >API >Synthetic Anti-infective Drugs >Antiviral drugs >2'-Deoxy-L-thymidine

2'-Deoxy-L-thymidine

2'-Deoxy-L-thymidine Structure
CAS No.
3424-98-4
Chemical Name:
2'-Deoxy-L-thymidine
Synonyms
Ldt;L-Dt;Sebivo;NV 02B;Epavudine;Aids112549;elbivudine;Aids-112549;L-Deoxythymidine;BETA-L-THYMIDINE
CBNumber:
CB4321891
Molecular Formula:
C10H14N2O5
Molecular Weight:
242.23
MOL File:
3424-98-4.mol
Modify Date:
2023/8/17 13:06:49
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2'-Deoxy-L-thymidine Properties

Melting point 188-190°C
alpha D20 -20.3° (c = 0.192 in water)
Density 1.452±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility H2O: soluble10mg/mL (clear solution)
pka 9.55±0.10(Predicted)
form powder
color white to beige
optical activity [α]/D -15 to -22°, c = 1 in H2O
InChIKey IQFYYKKMVGJFEH-CSMHCCOUSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
WGK Germany  3
RTECS  UV9048500
HS Code  29349990
NFPA 704
0
2 0

2'-Deoxy-L-thymidine price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0293 Telbivudine ≥98% (HPLC) 3424-98-4 5MG ₹12394.63 2022-06-14 Buy
Sigma-Aldrich(India) SML0293 Telbivudine ≥98% (HPLC) 3424-98-4 25MG ₹50076.45 2022-06-14 Buy
Product number Packaging Price Buy
SML0293 5MG ₹12394.63 Buy
SML0293 25MG ₹50076.45 Buy

2'-Deoxy-L-thymidine Chemical Properties,Uses,Production

Description

Telbivudine is a b-L-thymidine nucleoside analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is the fourth nucleoside or nucleotide analog to be marketed for this indication. The previous drugs from this class include lamivudine, a deoxythiacytosine analog, adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir, and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated by cellular kinases to the active triphosphate derivative, which inhibits HBV DNA polymerase by competing with the natural substrate, thymidine- 5’-triphosphate.

Chemical Properties

2'-Deoxy-L-thymidine is White Solid

Definition

ChEBI: A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.

2'-Deoxy-L-thymidine Preparation Products And Raw materials

Raw materials

Preparation Products

2'-Deoxy-L-thymidine Suppliers

Global( 310)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Maas Pharma Chemicals +91-9958666224 Delhi, India 1607 58 Inquiry
Avanscure Lifesciences Private Limited 09599609443 Haryana, India 66 58 Inquiry
Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group) 91-22-42361111 Maharashtra, India 147 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4223 58 Inquiry
Supplier Advantage
Clearsynth Labs 58
Pharma Affiliates 58
Maas Pharma Chemicals 58
Avanscure Lifesciences Private Limited 58
Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group) 58
CHEMSWORTH 30
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Reax Chemicals 58

2'-Deoxy-L-thymidine Spectrum

2'-Deoxy-L-thymidine(3424-98-4)1HNMR

3424-98-4(2'-Deoxy-L-thymidine)Related Search:

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2'-Deoxy-L-thymidine Deoxynucleotide Deoxidizer
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2'-Deoxy-L-thyMidine(Telbivudine) Telbivudine(Tyzeka, Sebivo) 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-Methyl- Telbivudine(L-ThyMidine,LDT-600) 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione 2,4(1H,3H)-PyriMidinedione,1-(2-deoxy-b-L-erythro-pentofuranosyl)-5-Methyl- Sebivo Telbivudine(L-ThyMidine) Telbivudine, >=98% 1-(2-Deoxy--L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione 1-(2-deoxy--L-erythro-pentofuranosyl)thymine Epavudine NV 02B Aids112549 Aids-112549 L-Deoxythymidine Ldt L-Dt Thymine, 1-(2-deoxy-.beta.-L-erythro-pentofuranosyl)- BETA-L-THYMIDINE 2'-DEOXY-L-THYMIDINE L-Thymidine(Telbivudine) 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione Β-L-2'-DEOXY-THYMIDINE 1-[(2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-methyl- elbivudine 2'-Deoxy-L-thymidine USP/EP/BP Telbivudine (Epavudine) Telbivudine 13C 15N2 Inhibitor,Telbivudine,inhibit,HBV,Hepatitis B virus 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 2'-Deoxy-L-thymidine 3424-98-4 Anti-virals Bases & Related Reagents Carbohydrates & Derivatives Intermediates & Fine Chemicals Nucleotides Pharmaceuticals API intermediates Amines API Chiral Reagents Heterocycles