C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT)

C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) Structure
CAS No.
127869-51-6
Chemical Name:
C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT)
Synonyms
CNP;CNP2;Human CNP-22;CNP-22, HUMAN;CNP(1-22)【human】;CNP(1-22)【porcine】;Atriopeptin C (pig);HuMan CNP-22 Peptide;GLSKGCFGLKLDRIGSMSGLGC;natriureticpeptide,c-type
CBNumber:
CB4349631
Molecular Formula:
C93H157N27O28S3
Molecular Weight:
2197.6
MOL File:
127869-51-6.mol
Modify Date:
2024/7/2 8:55:09

C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) Properties

Density 1.46±0.1 g/cm3(Predicted)
storage temp. −20°C
form White to off-white lyophilized solid
color White to off-white
Water Solubility Soluble in Water
Sequence H-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-OH(Disulfide bridge: Cys6-Cys11)

SAFETY

Risk and Safety Statements

WGK Germany  3

C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) N8768 Natriuretic Peptide, C-Type ≥95% (HPLC) 127869-51-6 0.1MG ₹11647.7 2022-06-14 Buy
Sigma-Aldrich(India) N8768 Natriuretic Peptide, C-Type ≥95% (HPLC) 127869-51-6 0.5MG ₹40344.78 2022-06-14 Buy
Sigma-Aldrich(India) 05-23-0310 Natriuretic Peptide, C-Type, Human and Porcine - CAS 127869-51-6 - Calbiochem Member of the natriuretic peptide family that shares structural homology with ANP and plays a role in the regulation of body fluid homeostasis, vascul 127869-51-6 .5MG ₹18980 2022-06-14 Buy
Sigma-Aldrich(India) 05-23-0310 Natriuretic Peptide, C-Type, Human and Porcine - CAS 127869-51-6 - Calbiochem Member of the natriuretic peptide family that shares structural homology with ANP and plays a role in the regulation of body fluid homeostasis, vascul 127869-51-6 1MG ₹33320.01 2022-06-14 Buy
Product number Packaging Price Buy
N8768 0.1MG ₹11647.7 Buy
N8768 0.5MG ₹40344.78 Buy
05-23-0310 .5MG ₹18980 Buy
05-23-0310 1MG ₹33320.01 Buy

C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) Chemical Properties,Uses,Production

General Description

Natriuretic Peptide, C-Type (NPPC/ CNP) is a 22 amino acid peptide encoded by NPPC gene mapped to human chromosome 2q37.1. It belongs to the natriuretic peptide family.

Biochem/physiol Actions

C-type natriuretic peptide is produced in the hypothalamus, anterior pituitary, and most major endocrine glands. It has potent venodilatory and coronary vasodilatory effects, but minimal effects on renal function.

Structure and conformation

Human proCNP consists of 103 aa residues with a bioactive mature CNP at the C-terminus. All four types of CNPs consist of 22 aa residues except for some teleost CNP4. Like other NPs, CNPs have a 17 aa intramolecular ring, but lack a C-terminal tail sequence. CNPs are the most conserved NPs, although they contain different groups of peptides. The sequence identity of mature CNP4 is >95% in mammals, except for unique CNP in the little brown bat (Myotis lucifugus). CNP1 and CNP3 are also well conserved (both >80% identity) in each vertebrate class that possesses both peptides. In contrast, CNP2 in teleosts is not so conserved. Although major CNPs are of different types among vertebrate classes, mature sequences are highly conserved among these CNPs, suggesting that CNPs have undergone convergent evolution.
Structure of CNPs

C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) Suppliers

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NATRIURETIC PEPTIDE, C-TYPE, HUMAN AND PORCINE GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS GLSKGCFGLKLDRIGSMSGLGC GLSKGCFGLKLDRIGSMSGLGC (DISULFIDE BRIDGE: 6-22) H-GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS-OH H-GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS-OH (DISULFIDE BRIDGE: 6-22) CNP CNP-22, HUMAN CNP-22, HUMAN, PORCINE, RAT CNP-22 (HUMAN) (PORCINE, RAT, MOUSE) CNP (32-53) (HUMAN, PORCINE, RAT) C-TYPE NATRIURETIC PEPTIDE-22 (HUMAN) (PORCINE, RAT, MOUSE) C-TYPE NATRIURETIC PEPTIDE (32-53), HUMAN, PORCINE C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE (1-22), HUMAN natriureticpeptide,c-type CNP(1-22)【human】 CNP(1-22)【porcine】 C-Type natriuretic peptide(1-22)【porcine】 C-Type natriuretic peptide【porcine】 C-Type natriuretic peptide【rat】 NATRIURETIC PEPTIDE, C-TYPE;CNP GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS(DISULFIDE BRIDGE:CYS6-CYS22) GLY-LEU-SER-LYS-GLY-CYS-PHE-GLY-LEU-LYS-LEU-ASP-ARG-ILE-GLY-SER-MET-SER-GLY-LEU-GLY-CYS: GLSKGCFGLKLDRIGSMSGLGCDISULFIDE BRIDGE CYS6-CYS22 Atriopeptin C (pig) C-type natriuretic peptide (1-22) (human, rat, swine) C-Type Natriuretic Peptide (32-53) (huMan, porcine, rat) CNP-22 (huMan, porcine, rat) Natriuretic Peptide, C-TypeNatriuretic Pepti C-TYPE NATRIURETIC PEPTIDE (PORCINE, RAT) HuMan CNP-22 Peptide C-Type natriuretic factor-22 (pig) Human CNP-22 Human C-type natriuretic peptide(1-22) Porcine C-type natriuretic peptide(1-22) Rat C-type natriuretic peptide(1-22) ANTI-NPPC (C-TERM) antibody produced in rabbit CNP2 Natriuretic peptide, C-Type, ≥95% (HPLC) Natriuretic Peptide, C-Type, Human and Porcine - CAS 127869-51-6 - Calbiochem C-Type Natriuretic Peptide (CNP) (1-22), human L-Cysteine, glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-, cyclic (6→22)-disulfide C-Type natriuretic factor-22(swine) seizure syndrome,hypertrophied kidney,C Type Natriuretic Peptide (CNP) (1 22), human,heart transplant,developing kidney,inhibit,CType Natriuretic Peptide (CNP) (122), human,CNP,cAMP synthesis,Inhibitor 127869-51-6 C93H157N27O28S3 Biochemicals and Reagents BioChemical Amino Acids and Peptides Peptides Natriuretic Peptides Peptide