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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Proteases >Cysteine ??Protease Inhibitors >E-64C

E-64C

E-64C Structure
CAS No.
76684-89-4
Chemical Name:
E-64C
Synonyms
E-64C;NSC 694279;E-64c, EP 475;Loxistatin acid;anecarboxylicacid;ep475(enzymeinhibitor);Loxistatin Acid (E-64C);Inhibitorforthiolprotease;NSC 694279 Loxistatin Acid;E-64-c Loxistatin acid NSC 694279
CBNumber:
CB4425580
Molecular Formula:
C15H26N2O5
Molecular Weight:
314.38
MOL File:
76684-89-4.mol
Modify Date:
2024/7/2 8:55:09
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E-64C Properties

storage temp. Sealed in dry,Store in freezer, under -20°C
solubility ≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
form White to off-white solid
color White to off-white
InChIKey SCMSYZJDIQPSDI-SRVKXCTJSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
RTECS  RR0404200
HS Code  29241990

E-64C Chemical Properties,Uses,Production

Description

E-64c is an active metabolite of the protease inhibitor E-64d . E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml. E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.

Uses

E-64c is a cysteine protease inhibitor used for detecting autophagy in plants.

E-64C Preparation Products And Raw materials

Raw materials

Preparation Products

E-64C Suppliers

Global( 113)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Supplier Advantage
Alpha Biopharmaceuticals Co., Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
Nextpeptide Inc 58
InvivoChem 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Aladdin Scientific 58

E-64C Spectrum

E-64C(76684-89-4)1HNMR

76684-89-4(E-64C)Related Search:

2-Hydroxy-4-amino butanoic acid (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID BUTTPARK 37\11-64 GLYCIDAMIDE EST
BUTTPARK 45\03-64 BUTTPARK 44\01-64 BUTTPARK 36\08-64 BUTTPARK 45\03-64 BUTTPARK 43\57-64
(2-amino-2-oxoethoxy)acetic acid E-64C (2-AMINO-ETHOXY)-ACETIC ACID 2(2-HYDROXYETHOXY)ACETAMIDE BUTTPARK 62\07-64
BUTTPARK 51\09-64 BUTTPARK 64\41-01 BUTTPARK 46\18-64
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(2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE (2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE (2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid 2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)- Loxistatin Acid (E-64C) NSC 694279 E-64c, EP 475 (1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCINE (3-METHYLBUTYL)AMIDE E-64C L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE (+)-(2s,3s)-3-((s)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxir (2s-(2-alpha,3-beta(r*)))-mino)carbonyl) anecarboxylicacid ep475(enzymeinhibitor) oxiranecarboxylicacid,3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)a (2S,3S)-TRANS-EPOXYSUCCINYL-L-*LEUCYLAMI DO-3-METHYL Inhibitorforthiolprotease (2S)-3β-[[[(S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2α-oxiranecarboxylic acid (2S,3S)-3-[[(1S)-1-(3-Methylbutylcarbamoyl)-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid Loxistatin acid E-64-c Loxistatin acid NSC 694279 NSC 694279 Loxistatin Acid NSC 694279 LOXISTATIN ACID; EP 475;E64C;E 64C 76684-89-4 BioChemical Calpain A to C Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme Enzyme Inhibitors Biochemicals and Reagents Pepetides Inhibitors peptides