ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Amine salt (ammonium salt) >N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Structure
CAS No.
132172-61-3
Chemical Name:
N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
Synonyms
DOTAP;DOTMA;dotap chloride;1,2-dioleoyl-3-trimethylammonium-propane (chloride salt);NSC8484;NSC 8484;NSC-8484;DOTAP-Cl;Lipofectin;18:1 TAP (DOTAP)
CBNumber:
CB4441795
Molecular Formula:
C42H80ClNO4
Molecular Weight:
698.56
MOL File:
132172-61-3.mol
MSDS File:
SDS
Modify Date:
2025/4/28 21:36:36

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Properties

Melting point 35-38°C
storage temp. -20°C
solubility Chloroform (Slightly)
form lyophilized powder
color White to Pale Yellow
Stability Store in Freezer, Hygroscopic
InChIKey KSXTUUUQYQYKCR-LQDDAWAPSA-M
SMILES C(C[N+](C)(C)C)(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC.[Cl-]

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements  P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
WGK Germany  3

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) D6182 DOTAP chloride ≥98% (TLC), powder 132172-61-3 50MG ₹37140.58 2022-06-14 Buy
Sigma-Aldrich(India) D6182 DOTAP chloride ≥98% (TLC), powder 132172-61-3 250MG ₹99968.88 2022-06-14 Buy
Product number Packaging Price Buy
D6182 50MG ₹37140.58 Buy
D6182 250MG ₹99968.88 Buy

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White Foam

Uses

Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of DNA. Facilitates fusion of the complex with the plasma membrane of tissue culture cells, resulting in both uptake and

Biochem/physiol Actions

18:1 TAP (DOTAP) is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP(1,2-dioleoyl-3-trimethylammonium-propane). 18:1 TAP (DOTAP) mediates gene knockdown technique in hematopoietic stem cells (HSCs).

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 164)Suppliers
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1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE, CHLORIDE DOTAP CHLORIDE SALT N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE N-[1-(2,3-DIOLEOYLOXY)PROPYL]-N,N,N-TRIMETHYL-AMMONIUM CHLORIDE SALT N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE TRIMETHYL[2,3-(DIOLEYLOXY)PROPYL]AMMONIUM CHLORIDE 2,3-Bis(oleoyloxy)-N,N,N-trimethyl-1-propanaminium 3-(Trimethylaminio)propane-1,2-diol 1,2-bis[(Z)-9-octadecenoate] Lipofectin N-[2,3-Bis(oleoyloxy)propyl]-N,N-dimethylmethanaminium N-[2,3-Di(oleoyloxy)propyl]-N,N,N-trimethylaminium N,N,N-TriMethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-1-propanaMiniuM DOTAP;DOTAP, CHLORIDE 18:1 TAP (DOTAP) 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium (2,3-Dioleyl-propyl) -trimethylamine N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-, chloride (1:1) NSC 8484 NSC8484 NSC-8484 DOTMA DOTAP dotap chloride 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) DOTAP-Cl N-(2,3-Dioleoyloxy)propyl-N,N,N-trimethylammonium Chloride DOTAP (chloride salt) (2,3-dioleoyl-propyl) - trimethylamine (chloride salt) DOTAP chloride, 10 mM in DMSO 132172-61-3 C42H80ClNO4 C40H80ClNO2 Ammonium Chlorides (Quaternary) Quaternary Ammonium Compounds BioChemical Cloning and Expression Molecular Biology Transfection & Transformation Fatty Acid Derivatives & Lipids Glycerols Mixed Fatty Acids