(S)-(-)-PROPRANOLOL HYDROCHLORIDE
![(S)-(-)-PROPRANOLOL HYDROCHLORIDE Structure](CAS/GIF/4199-10-4.gif)
- CAS No.
- 4199-10-4
- Chemical Name:
- (S)-(-)-PROPRANOLOL HYDROCHLORIDE
- Synonyms
- S-PROPANOLOL;S-(-)-PROPANOLOL HCL;S(-)-PROPRANOLOL HCL;l-Propranolol chlorhydrate;l-Propranolol hydrochloride;(S)-PROPRANOLOL HYDROCHLORIDE;Levopropranolol hydrochloride;L-(-)-Propranolol hydrochloride;2S-(-)-PROPANOLOL HYDROCHLORIDE;(S)-(-)-PROPRANOLOL HYDROCHLORIDE
- CBNumber:
- CB4455695
- Molecular Formula:
- C16H22ClNO2
- Molecular Weight:
- 295.8
- MOL File:
- 4199-10-4.mol
- Modify Date:
- 2024/8/1 17:24:36
Melting point | 193-195 °C(lit.) |
---|---|
storage temp. | 2-8°C |
solubility | ethanol: 10 mg/mL |
form | powder |
color | White to off-white |
optical activity | [α]25/D 25.5°, c = 1.0 in ethanol(lit.) |
Water Solubility | Soluble to 100 mM in water |
BRN | 3574966 |
InChIKey | ZMRUPTIKESYGQW-UQKRIMTDSA-N |
CAS DataBase Reference | 4199-10-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332 | |||||||||
Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 20/21/22 | |||||||||
Safety Statements | 36 | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
|
(S)-(-)-PROPRANOLOL HYDROCHLORIDE price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P8688 | (S)-(−)-Propranolol hydrochloride ≥98% (TLC), powder | 4199-10-4 | 100MG | ₹12946.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P8688 | (S)-(−)-Propranolol hydrochloride ≥98% (TLC), powder | 4199-10-4 | 500MG | ₹43451.55 | 2022-06-14 | Buy |
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Chemical Properties,Uses,Production
Description
(S)-(-)-Propranolol is the active enantiomer of propranolol, a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. It is also a non-specific serotonin receptor antagonist. Propanolol was one of the first β-adrenergic receptor blockers to be widely used in clinical practice for the treatment of hypertension, angina pectoris, and cardiac ischemia.
Chemical Properties
(S)-(-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
Uses
The S-enantiomer of Propranolol (P831800). β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
Biological Activity
More active enantiomer of the β -adrenoceptor antagonist propranolol ((RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride ).
Purification Methods
The (+)-salt is the active isomer which blocks isoprenaline tachycardia and is a -adrenergic blocker. [Leclerc et al. Trends Pharmacol Sci 2 18 1981, Howe & Shanks Nature 210 1336 1966.]
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | 18192627656 | China | 2673 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | CHINA | 9427 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
Supplier | Advantage |
---|---|
A.J Chemicals | 58 |
SynZeal Research Pvt Ltd | 58 |
Shaanxi Dideu Medichem Co. Ltd | 58 |
Capot Chemical Co.,Ltd. | 60 |
ATK CHEMICAL COMPANY LIMITED | 60 |
TargetMol Chemicals Inc. | 58 |
Career Henan Chemica Co | 58 |
Baoji Guokang Healthchem co.,ltd | 58 |
BOC Sciences | 58 |
Nextpeptide Inc | 58 |
4199-10-4((S)-(-)-PROPRANOLOL HYDROCHLORIDE)Related Search:
1of4
chevron_right