2,4,6-TRIACETYLPHLOROGLUCINOL
- CAS No.
- 2161-87-7
- Chemical Name:
- 2,4,6-TRIACETYLPHLOROGLUCINOL
- Synonyms
- Triacetylphloroglucinol;Phloroglucinol Triacetyl;Penicillamine Impurity 19;2,4,6-TRIACETYLPHLOROGLUCINOL ;Phloroglucinol 2,4,6-Triacetate;2,4,6-Triacetyl-1,3,5-trihydroxybenzene;1,3,5-triacetyl-2,4,6-trihydroxybenzene;Ethanone, 1,1',1''-(2,4,6-trihydroxy-1,3,5-benzenetriyl)tris-;1,1',1''-(2,4,6-trihydroxybenzene-1,3,5-triyl)tris(ethan-1-one);1,1',1''-(2,4,6-trihydroxybenzene-1,3,5-triyl)tris(ethan-1-one)
- CBNumber:
- CB4496881
- Molecular Formula:
- C12H12O6
- Molecular Weight:
- 252.22
- MOL File:
- 2161-87-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
2,4,6-TRIACETYLPHLOROGLUCINOL Chemical Properties,Uses,Production
Description
Triacetylphloroglucinol is a C3-symmetric tritopic bridging ligand. It has been used in the synthesis of various compounds, including trinuclear vanadium Schiff base complexes, copper complexes, and anthelmintics.
Chemical Properties
Beige Needles
Uses
Triacetylphloroglucinol (TAPG) is the most hydrophobic of a small molecular weight phenolic metabolite belonging to the phloroglucinol (1,3,5 trihydroxybenzene) family, produced by bacteria including Pseudomonas strains. TAPG exhibits a broad range of biological activities, albeit with mostly low potency. In the search for novel actives, TAPG and related metabolites are important for dereplication to eliminate leads due to high amounts of weakly potent actives. Although weakly active, this family appears to be important in the biocontrol of plant diseases by some Pseudomonas strains.
Preparation
Obtained by Friedel–Crafts acylation of phloroglucinol,
? with acetic anhydride in the presence of boron trifluoride in acetic acid at r.t. (60%)
; ? with acetyl chloride in the presence of aluminium chloride in ethyl ether at r.t. for 6 days (17%)
; ? with acetyl chloride and acetic acid in the presence of ferric chloride in ethyl acetate.
2,4,6-TRIACETYLPHLOROGLUCINOL Preparation Products And Raw materials
2,4,6-TRIACETYLPHLOROGLUCINOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 13164 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | China | 42057 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Shanghai Aocheng Biological Technology Co., Ltd. | 13917627064 | China | 571 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 41844 | 58 | Inquiry |
| Chongqing Xinboyao Biological Technology Co., LTD | 19122915778 | China | 299 | 58 | Inquiry |