Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >API >Antibiotics >Other antibiotic Drugs >Novobiocin

Novobiocin

Novobiocin Structure
CAS No.
303-81-1
Chemical Name:
Novobiocin
Synonyms
inamycin;pa93;U 6391;novo-r;C05080;albamix;cathocin;robiocina;NOVOBIOCIN;cathomycin
CBNumber:
CB4500553
Molecular Formula:
C31H36N2O11
Molecular Weight:
612.62
MOL File:
303-81-1.mol
MSDS File:
SDS
Modify Date:
2024/5/11 20:10:50
Request For Quotation

Novobiocin Properties

Melting point 170-172 °C
alpha D24 -63.0° (c = 1 in ethanol)
Boiling point 657.29°C (rough estimate)
Density 1.3448
refractive index 1.5800 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka pKa1 4.3; pKa2 9.1(at 25℃)
color White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P301+P312+P330
WGK Germany  3
HS Code  2941906000

Novobiocin Chemical Properties,Uses,Production

Chemical Properties

A light-yellow to white antibiotic produced by Streptomyces niveus. Available as calcium and sodium salts.

Uses

Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram positive activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and a competitive inhibitor of the ATPase reaction catalysed by GyrB.

Definition

ChEBI: A coumarin-derived antibiotic obtained from Streptomyces niveus.

World Health Organization (WHO)

Novobiocin, an antibiotic with a narrow spectrum of activity, was introduced in 1956. Its use was subsequently associated with serious adverse effects including blood dyscrasias. In view of its toxicity there are no current valid indications for its use. Although preparations containing novobiocin may remain available in some countries it has largely lapsed into disuse.

Hazard

May have damaging side effects.

Novobiocin Preparation Products And Raw materials

Raw materials

SOYBEAN MEAL D(+)-Glucose

Preparation Products

Novobiocin Suppliers

Global( 81)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
ZHEJIANG JIUZHOU CHEM CO., LTD +86-0576225566889 +86-13454675544 China 12272 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +86-19164747840 +86-13119157289 China 2969 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Shaanxi Dideu Medichem Co. Ltd 58
BOC Sciences 58
Nantong HI-FUTURE Biology Co., Ltd. 58
ZHEJIANG JIUZHOU CHEM CO., LTD 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 58
Aladdin Scientific 58

Related articles

303-81-1(Novobiocin)Related Search:

3-ACETAMIDOCOUMARIN n-Butyl carbamate 3-METHYLHIPPURIC ACID 4-Hydroxycoumarin 2-Acetamidoacrylic acid
MEPHENESIN 4-METHOXY-3-METHYLBENZYL ALCOHOL Methyl 2-acetamidoacrylate Novobiocin 3-AMINOCOUMARIN
2-(Acetylamino)-3-phenyl-2-propenoic acid CHEMBRDG-BB 9071689 4,7-DIHYDROXYCOUMARIN CHEMBRDG-BB 9071067 2-(2-methylphenoxy)ethanamine
hedonal CHEMBRDG-BB 9070842 CHEMBRDG-BB 9071793
chevron_left

1of4

chevron_right
NOVOBIOCIN cathocin cathomycin crystallinicacid -hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2h-1-benzopyran-3-yl)-4-hydroxy- novo-r pa93 U 6391 3-(3-methyl-2-butenyl)- albamix antibioticpa-93 benzamide,n-(7-((3-o-(aminocarbonyl)-6-deoxy-5-c-methyl-4-o-methyl-beta-l-lyxo cardelmycin robiocina sirbiocina spheromycin stilbiocina NOVOBIOCIN (200 MG)H0D3271012UG/MG(DR) NOVOBIOCIN, USP STANDARD 7-[4'-(Carbamoyloxy)-tetrahydro-3'-hydroxy-5'-methoxy-6',6'-dimethylpyran-2'-yloxy]-4-hydroxy-3-[4''-hydroxy (3''-methyl-2''-butenyl)-benzamide]-8-methylcoumarin C05080 Novobiocin (200 mg) AlbaMycin, VulcaMycin, PA 93, WS 6629, Griseoflavin, S 800. Benzamide, N-[7-[[3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-buten-1-yl)- Novobiocin powder Novobiocin USP/EP/BP (3R,4S,5R,6R)-5-Hydroxy-6-((4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yl)oxy)-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate Novobiocin (1475008) inamycin 303-81-1