2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER
![2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER Structure](CAS/GIF/415697-08-4.gif)
- CAS No.
- 415697-08-4
- Chemical Name:
- 2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER
- Synonyms
- SN-6;SN-6;SN6;SN 6;inhibit,SN 6,Na+/Ca2+ Exchanger,SN-6,Inhibitor;Ethyl 2-(4-((4-nitrobenzyl)oxy)benzyl)thiazolidine-4-carboxylate;2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER;4-Thiazolidinecarboxylic acid, 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-, ethyl ester
- CBNumber:
- CB4690807
- Molecular Formula:
- C20H22N2O5S
- Molecular Weight:
- 402.46
- MOL File:
- 415697-08-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:09
| Boiling point | 581.2±50.0 °C(Predicted) |
|---|---|
| Density | 1.285±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO : 62.5 mg/mL (155.29 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| pka | 6.63±0.60(Predicted) |
| color | White to light yellow |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER Chemical Properties,Uses,Production
Biological Activity
Selective Na + /Ca 2+ -exchange (NCX) inhibitor; displays some selectivity for NCX1. IC 50 values are 2.9, 16 and 8.6 μ M for inhibition of intracellular Na+-dependent 45 Ca 2+ uptake by cells expressing NCX1, NCX2 and NCX3 respectively. Has some affinity for mACh receptors (IC 50 = 18 μ M) but minimal activity against NCKX2 and various receptors and ion channels (IC 50 > 30 μ M). Preferentially blocks Ca 2+ influx mode and is more selective for NCX isoforms than KB-R7943 (2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothioureamesylate ). Anti-ischemic; potently protects against hypoxia-induced renal tubular cell damage (IC 50 = 0.63 μ M).
2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 68)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Xiamen Huijia Biological Technology Co., Ltd. | 0592-6020891 | CHINA | 6979 | 58 | Inquiry |
| Shanghai Yubo Biotechnology Co., Ltd. | 021-51875103 15026509758 | CHINA | 6322 | 58 | Inquiry |
| Guangzhou Weijia Technology Co., Ltd. | 020-84224925 18300190102 | CHINA | 6748 | 58 | Inquiry |
415697-08-4(2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER)Related Search:
SN-6
2-[[4-[(4-NITROPHENYL)METHOXY]PHENYL]METHYL]-4-THIAZOLIDINECARBOXYLIC ACID ETHYL ESTER
SN-6;SN6;SN 6
4-Thiazolidinecarboxylic acid, 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-, ethyl ester
Ethyl 2-(4-((4-nitrobenzyl)oxy)benzyl)thiazolidine-4-carboxylate
inhibit,SN 6,Na+/Ca2+ Exchanger,SN-6,Inhibitor
415697-08-4
Ion transporter and other ion channel