1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE Structure
CAS No.
67469-57-2
Chemical Name:
1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE
Synonyms
CS-1338;GBR-12783;GBR 12921;GBR127832HCl;GBR 12783 DIHYDROCHLORIDE;1-(2-(Benzhydryloxy)ethyl)-4-cinnamylpiperazine;1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)piperazine;Piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)-;1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenyl-2-propen-1-yl)piperazine;Piperazine, 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propen-1-yl)-
CBNumber:
CB4726281
Molecular Formula:
C28H32N2O
Molecular Weight:
412.57
MOL File:
67469-57-2.mol
Modify Date:
2023/5/9 9:30:42

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE Properties

Melting point >200°C (dec.)
Boiling point 551℃
Density 1.085
Flash point 148℃
storage temp. Desiccate at -20°C
solubility Methanol (Slightly), Water (Slightly, Heated)
form Solid
color White to Off-White

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

GBR 12783 is a very potent and selective inhibitor of dopamine uptake.

Biological Activity

A very potent and selective inhibitor of dopamine uptake (IC 50 for inhibition of [ 3 H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM).

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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Piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)- 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE GBR 12783 DIHYDROCHLORIDE GBR127832HCl GBR 12921 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)piperazine GBR-12783 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenyl-2-propen-1-yl)piperazine 1-[2-(diphenylMethoxy)ethyl]-4-(3-phenylprop-2-en-1-yl)piperazine dihydrochloride CS-1338 1-(2-(Benzhydryloxy)ethyl)-4-cinnamylpiperazine Piperazine, 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propen-1-yl)- 67469-57-2 C28H32N2O2HCl Dopamine receptor