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Carotene

Carotene Structure
CAS No.
7488-99-5
Chemical Name:
Carotene
Synonyms
C05433;Carotene;A-CAROTENE;α-Carotene;Renieratene;CAROTENE, A-;ALPHA-CAROTENE;Isorenieratene;CAROTENE, ALPHA-;CISALPHA-CAROTENE
CBNumber:
CB4784043
Molecular Formula:
C40H56
Molecular Weight:
536.89
MOL File:
7488-99-5.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:09

Carotene Properties

Melting point 187.50° (evacuated tube)
alpha 18643 +385° (c = 0.08 in benzene)
Boiling point 644.94°C (rough estimate)
Density 0.9380 (estimate)
refractive index 1.5630 (estimate)
storage temp. -20°C
solubility Chloroform (Slightly)
form Solid
color Orange to Very Dark Orange
Odor Slight characteristic
λmax λ: 445-449 nm Amax
BRN 3227603
Stability Light Sensitive, Temperature Sensitive

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  40-67-36/37/38
Safety Statements  36/37-24/25-23
RIDADR  UN 1593 6.1/PG 3
WGK Germany  3
HS Code  32041990

Carotene price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 50887 α-Carotene analytical standard 7488-99-5 1MG ₹73182.3 2022-06-14 Buy
Sigma-Aldrich(India) 40395 α-Carotene ≥95.0% (HPLC) 7488-99-5 1MG ₹70274.1 2022-06-14 Buy
Product number Packaging Price Buy
50887 1MG ₹73182.3 Buy
40395 1MG ₹70274.1 Buy

Carotene Chemical Properties,Uses,Production

Description

α-Carotene is a precursor of vitamin A that has been found in various fruits and vegetables. It inhibits proliferation of GOTO human neuroblastoma cells more potently than β-carotene and halts the cell cycle at the G0/G1 phase concomitantly with a reduction in the mRNA expression of the protooncogene N-Myc. It is also more potent than β-carotene in mouse models of skin and lung carcinogenesis and decreases the number of hepatomas in mice with spontaneous liver carcinogenesis when administered in drinking water at a concentration of 0.05%. α-Carotene levels are increased in patients with coronary heart disease and are inversely correlated with the risk of estrogen receptor-negative breast cancer.

Uses

carotene is used to provide a red-orange color in cosmetic formulations. It is the primary yellow coloring component of butter, carrots, and egg yolk. Carotene is found in plants as well as in many animal tissues.

General Description

α-Carotene is a carotenoid, which shows anticarcinogenic activity.

Purification Methods

Purify α-carotene by chromatography on columns of calcium hydroxide, alumina or magnesia. Crystallise it from CS2/MeOH, toluene/MeOH, diethyl ether/pet ether, or acetone/pet ether. Store it in the dark, under N2 or Ar at -20o. It gives a blue colour with max at 542nm when mixed with SbCl3 in CHCl3. [Karrer & Walker Helv Chim Acta 16 641 1933, Eugster et al. Helv Chim Acta 52 1729 1969, Eugster & Karrer Helv Chim Acta 38 610 1955, Strain J Biol Chem 105 523 1934, Beilstein 5 III 2457, 5 IV 2620.]

Carotene Preparation Products And Raw materials

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A-CAROTENE ALPHA/BETA-CAROTENE MIX ALPHA-CAROTENE CAROTENE, A- ALPHA-CAROTENE FROM CARROTS .beta.,.epsilon.-Carotene, (6R)- CAROTENE, ALPHA- (1.0Mg/ML)(DICHLOROMETHANE)(SH) (6'R)-beta,epsilon-carotene -Carotene(natural) (6'R)-b,e-Carotene all-trans-a-Carotene Renieratene Isorenieratene (6'R)-β,ε-Carotene C05433 CAROTENE, ALPHA- 0.66mg/mL(CHLOROFORM)(SH) CAROTENE,ALPHA-(SH)(PLEASECALL) (1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-1-(2,6,6-trimethyl-1-cyclohexenyl)-18-(2,6,6-trimethyl-1-cyclohex-2-enyl)octadeca-1,3,5,7,9,11,13,15,17-nonaene CISALPHA-CAROTENE TRANSALPHA-CAROTENE Carotene R(+)-alpha-Carotene α-Carotene solution (6’R)-,e-Carotene α-Carotene Standard Carotene USP/EP/BP α-Carotene β,ε-Carotene, (6'R)- α-Carotene Standard α-Carotene (natural) (6'R)-β,ε-carotene CAROTENE, ALPHA- 7488-99-5 156-1-28 Alphabetic C Food&Beverage Standards Life Sciences Standards Natural Compounds Natural CompoundsChemical Class CA - CGChromatography OtherChromatography Vitamins/CoFactors/Enzymes Miscellaneous Natural Products