Pyrene
- CAS No.
- 129-00-0
- Chemical Name:
- Pyrene
- Synonyms
- Pyren;Pyene;Pyrenepract;PYRENE;PTRENE;Pyreme;pyrene5;DYPR0414;Pyrene>Pyrene RS
- CBNumber:
- CB4853011
- Molecular Formula:
- C16H10
- Molecular Weight:
- 202.25
- MOL File:
- 129-00-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/4 15:29:52
| Melting point | 148 °C |
|---|---|
| Boiling point | 393 °C |
| Density | 1.271 |
| vapor pressure | 180 at 25 °C (extrapolated from vapor pressures determined at higher temperatures, Tesconi andYalkowsky, 1998) |
| refractive index | 1.8520 (estimate) |
| Flash point | 210 °C |
| storage temp. | room temp |
| solubility | ethanol: soluble |
| pka | >15 (Christensen et al., 1975) |
| form | crystalline |
| Specific Gravity | 1.271 |
| color | Pale yellow to yellow-greenish |
| Water Solubility | almost insoluble |
| λmax | 330nm(EtOH)(lit.) |
| Merck | 14,7963 |
| BRN | 1307225 |
| Henry's Law Constant | 0.490 at 25 °C (thermodynamic method-GC/UV spectrophotometry, Altschuh et al., 1999) |
| Exposure limits | OSHA: TWA 0.2 mg/m3 |
| InChIKey | BBEAQIROQSPTKN-UHFFFAOYSA-N |
| LogP | 5.43 at 30℃ and pH5-8 |
| CAS DataBase Reference | 129-00-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyrene(129-00-0) |
| IARC | 3 (Vol. Sup 7, 92) 2010 |
| EPA Substance Registry System | Pyrene (129-00-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H410 | |||||||||
| Precautionary statements | P273-P391-P501 | |||||||||
| Hazard Codes | N,T+,T,F,Xn | |||||||||
| Risk Statements | 50/53-36/37/38-26-39/23/24/25-23/24/25-11-63-43-45-67-65-38-51/53-52/53-40 | |||||||||
| Safety Statements | 60-61-45-36/37-28A-22-16-7-24/25-23-53-62-26 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UR2450000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29349990 | |||||||||
| Toxicity | LD50 orally in Rabbit: 2700 mg/kg | |||||||||
| NFPA 704 |
|
Pyrene price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 82648 | Pyrene puriss. p.a., for fluorescence, ≥99.0% (GC) | 129-00-0 | 1G | ₹2424.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21051 | Pyrene for synthesis | 129-00-0 | 5G | ₹5360 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 82648 | Pyrene puriss. p.a., for fluorescence, ≥99.0% (GC) | 129-00-0 | 10G | ₹12155.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21051 | Pyrene for synthesis | 129-00-0 | 50G | ₹10800 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21051 | Pyrene for synthesis | 129-00-0 | 250G | ₹46400 | 2022-06-14 | Buy |
Pyrene Chemical Properties,Uses,Production
Chemical Properties
Pyrene is a colorless crystalline solid when pure or pale yellow plates (impure). Polycyclic aromatic hydrocarbons (PAHs) are compounds containing multiple benzene rings and are also called polynuclear aromatic hydrocarbons. Solids and solutions have a Blue fluores- cence (Merck Index).
Physical properties
Colorless solid (tetracene impurities impart a yellow color) or monoclinic prisms crystallized from alcohol. Solutions have a slight blue fluorescence.
Uses
Pyrene occurs in coal tar. Also obtained by the destructive hydrogenation of hard coal. Found in wastewater in aquatic environments, and possesses genotoxic characteristics relating to estrogenic/andr ogenic, antiestrogenic and antiandrogenic activity.
Production Methods
There is no commercial production or known use for this compound. Pyrene has been used as starting material for the synthesis of benzo[a]pyrene.
Definition
A condensed ring hydro- carbon.
General Description
Colorless solid, solid and solutions have a slight blue fluorescence. Used in biochemical research.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Pyrene reacts with nitrogen oxides to form nitro derivatives. Pyrene also reacts with 70% nitric acid.
Hazard
A questionable carcinogen, absorbed by skin.
Health Hazard
Pyrene is a carcinogenic agent and is absorbed by the skin. It is a skin irritant, a suspected mutagen, and an equivocal tumor-causing agent. Workers exposed to 3 to 5 mg/m3 of Pyrene exhibited some teratogenic effects. Pyrene is a polycyclic aromatic hydrocarbon (PAH). The acute toxicity of pure PAHs appears low when administered orally or dermally to rats or mice. Human exposure to PAHs is almost exclusively via the gastrointestinal and respiratory tracts, and approximately 99 percent is ingested in the diet. Despite the high concentrations of Pyrene to which humans may be exposed through food, there is currently little information available to implicate diet-derived PAHs as the cause of serious health effects.
Fire Hazard
When heated to decomposition, Pyrene emits acrid smoke and fumes.
Safety Profile
Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. A sh irritant. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Potential Exposure
Pyrene is used as an industrial chemi- cal and in biochemical research.
Carcinogenicity
Pyrene was inactive as a tumor initiator. Based on inadequate animal data and no human data, the IARC classified pyrene as group 3, not classifiable as to its carcinogenicity to humans, and IRIS classified pyrene as a class D compound. Pyrene is present as a major component of the total content of PAHs in the environment. Exposure occurs primarily through tobacco smoke, inhalation of polluted air, and by ingestion of food and water.
Shipping
UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz- ardous material, Technical Name Required.
Purification Methods
Crystallise pyrene from EtOH, glacial acetic acid, *benzene or toluene. Purify it also by chromatography of CCl4 solutions on alumina, with *benzene or n-hexane as eluent. [Backer & Whitten J Phys Chem 91 865 1987.] It can also be zone refined and purified by sublimation. Marvel and Anderson [J Am Chem Soc 76 5434 1954] refluxed pyrene (35g) in toluene (400mL) with maleic anhydride (5g) for 4days, then added 150mL of aqueous 5% KOH and refluxed for 5hours with occasional shaking. The toluene layer was separated, washed thoroughly with H2O, concentrated to about 100mL and allowed to cool. Crystalline pyrene was filtered off and recrystallised three times from EtOH or acetonitrile. [Chu & Thomas J Am Chem Soc 108 6270 1986, Russell et al. Anal Chem 50 2961 1986.] The material is free from anthracene derivatives. Another purification step involves passage of pyrene in cyclohexane through a column of silica gel. It can be sublimed in a vacuum and zone refined. The picrate has m 224o. [Kano et al. J Phys Chem 89 3748 1985, Beilstein 5 IV 2467.]
Incompatibilities
Pyrene Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Pyrene reacts with nitrogen oxides to form nitro derivatives. It also reacts with 70% nitric acid
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed .
Pyrene Preparation Products And Raw materials
Raw materials
Preparation Products
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| AnalyticsStanza Inc | +91-7032031309 +91-7032031309 | Hyderabad, India | 227 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1843 | 58 | Inquiry |
| Siddh Interchem | 91-22-25084141 | Mumbai, India | 23 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| AnalyticsStanza Inc | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| HiMedia Laboratories | 58 |
| Siddh Interchem | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
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