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benzatropine

benzatropine Structure
CAS No.
86-13-5
Chemical Name:
benzatropine
Synonyms
Benaztropine;NK 02;Akitan;C06846;Cogentine;NISTC86135;benzatropine;exo-Benztropine;GIJXKZJWITVLHI-PMOLBWCYSA-N;(1S,5R)-3α-(Diphenylmethoxy)tropane
CBNumber:
CB4875758
Molecular Formula:
C21H25NO
Molecular Weight:
307.4293
MOL File:
86-13-5.mol
Modify Date:
2022/12/21 16:56:50

benzatropine Properties

Boiling point 447.93°C (rough estimate)
Density 1.0505 (rough estimate)
refractive index 1.5614 (estimate)
pka 10.54±0.40(Predicted)
EPA Substance Registry System 8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-methyl-, (3-endo)- (86-13-5)

SAFETY

Risk and Safety Statements

Toxicity LD50 scu-mus: 60 mg/kg JMPCAS 4,215,61

benzatropine Chemical Properties,Uses,Production

Uses

Antiparkinsonian.

Definition

ChEBI: Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to re uce parkinsonism and akathisia side effects of antipsychotic treatments.

Safety Profile

Poison by subcutaneous andintravenous routes. When heated to decomposition itemits toxic fumes of NOx.

benzatropine Preparation Products And Raw materials

Raw materials

Preparation Products

benzatropine Suppliers

Global( 13)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Shaanxi Didu New Materials Co. Ltd +86-89586680 +86-13289823923 China 9003 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24016 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4476 58 Inquiry
Shanghai Tachizaki Biomedical Research Center 18014399201 China 2532 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9282 58 Inquiry
benzatropine NISTC86135 (1S,5R)-3α-(Diphenylmethoxy)tropane exo-Benztropine (1β,3α,5β)-3-(Diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane (1β,5β)-3α-(Diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane C06846 GIJXKZJWITVLHI-PMOLBWCYSA-N 8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-methyl-, (3-endo)- Akitan Cogentine NK 02 Benaztropine 86-13-5