Cilofungin

Cilofungin Structure
CAS No.
79404-91-4
Chemical Name:
Cilofungin
Synonyms
LY-121019;Cilofungin;Cilofungin (9CI);Antibiotic LY-121019;(4R,5R)-N2-[4-(Octyloxy)benzoyl]-4,5-dihydroxycyclo[L-Orn*-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]];Cyclo[L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]];Cyclo[L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-]
CBNumber:
CB51120171
Molecular Formula:
C49H71N7O17
Molecular Weight:
1030.13
MOL File:
79404-91-4.mol
Modify Date:
2023/4/23 13:52:06

Cilofungin Properties

Melting point >165°C (dec.)
Boiling point 1397.0±65.0 °C(Predicted)
Density 1.46
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.86±0.26(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic

Cilofungin Chemical Properties,Uses,Production

Uses

Cilofungin is a lipopeptide from echinocandin class of antifungal drugs which inhibits the synthesis of glucan in the fungal cell walls.

Definition

ChEBI: A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycoti agent against Candida albicans.

Cilofungin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 10)Suppliers
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Nanjing Peptide Biotech Ltd. 025-025-58361106-805-805 13082558573 China 9962 55 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Cilofungin (4R,5R)-N2-[4-(Octyloxy)benzoyl]-4,5-dihydroxycyclo[L-Orn*-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]] Antibiotic LY-121019 Cyclo[L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-] Cyclo[L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]] LY-121019 Cilofungin (9CI) 79404-91-4 C49H71N7O17