dendrobine
- CAS No.
- 2115-91-5
- Chemical Name:
- dendrobine
- Synonyms
- Dendrobine 1%;(-)-Dendrobine;12-Oxodendrobane;Dendroban-12-one;Dendrobine 2115-91-5;From Dendrobium nobile;Dendrobine Dendroban-12-one;(3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one;(3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one;Dendrobine, 98%, from Dendrobium nobile Lindl
- CBNumber:
- CB51331533
- Molecular Formula:
- C16H25NO2
- Molecular Weight:
- 263.38
- MOL File:
- 2115-91-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:10
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
HS Code | 29399990 | |||||||||
NFPA 704 |
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dendrobine Chemical Properties,Uses,Production
Description
Dendrobine is a sesquiterpenoid that has been found in D. nobile and has anticancer activity. It decreases viability of A549 cells when used at concentrations ranging from 2.5 to 15 μg/ml. It induces apoptosis in A549 cells when used at concentrations ranging from 1 to 10 μg/ml, as well as increases JNK phosphorylation and sensitizes A549 cells to cisplatin at 10 μg/ml. Dendrobine (50 mg/kg per day) reduces tumor growth in an A549 mouse xenograft model with an additive effect when used in combination with cisplatin.
Uses
Dendrobine is an alkaloid isolated from Dendrobium nobile and is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord.
dendrobine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 174)Suppliers
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Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
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2115-91-5(dendrobine)Related Search:
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(3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one
Dendroban-12-one
12-Oxodendrobane
7,5-(EpoxyMethano)-1H-cyclopent[cd]indol-9-one,decahydro-1,7b-diMethyl-6-(1-Methylethyl)-, (2aS,4aS,5R,6S,7R,7aS,7bR)-
Dendrobine
Dendroban-12-one
Dendrobine 1%
Dendrobine, 98%, from Dendrobium nobile Lindl
Dendrobine 2115-91-5
From Dendrobium nobile
(3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one
(-)-Dendrobine
(2aS,2a1R,4aS,5R,8R,8aS,9S)-9-isopropyl-1,2a1-dimethyloctahydro-1H-7-oxa-1-aza-5,8-methanocyclopenta[cd]azulen-6(2a1H)-one
(2aS,2a1R,4aS,5R,8R,8aS,9S)-9-Isopropyl-2a1,4-dimethyldecahydro-7H-6-oxa-4-aza-5,8-methanocyclopenta[cd]azulen-7-one
2115-91-5
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract