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L-Homocystine

CAS No.: 626-72-2

Chemical Name:: L-Homocystine

Synonyms: (2S,2'S)-4,4'-Disulfanediylbis(2-aMinobutanoic acid);H-HoCys-OH;(H-HCY-OH)2;(H-Hcy-OH)?;H-L-HCystine;(H-HOCYS-OH)2;H-L-HOCYSTINE;(H-Hcys-OH) 2;L-Homocystine;L-Homocystine

CBNumber:: CB5155903

Molecular Formula:: C8H16N2O4S2

Molecular Weight:: 268.35

MOL File:: 626-72-2.mol

Modify Date:: 2024/7/2 8:55:11

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L-Homocystine Properties

Melting point	281-284 °C (dec.)(lit.)
alpha	77 º (c=1% in 1N HCl)
Boiling point	507.6±50.0 °C(Predicted)
Density	1.443±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	H2O : 5 mg/mL (18.63 mM; ultrasonic and adjust pH to 3 with H2O)DMSO : 1 mg/mL (3.73 mM; ultrasonic and adjust pH to 5 with HCl)
form	Powder
pka	1.90±0.10(Predicted)
color	Off-white to light yellow
BRN	1728583
InChIKey	ZTVZLYBCZNMWCF-WDSKDSINSA-N
CAS DataBase Reference	626-72-2(CAS DataBase Reference)
EPA Substance Registry System	L-Homocystine (626-72-2)

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3
HS Code	29309090

L-Homocystine price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	H6010	L-Homocystine ≥98% (HPLC)	626-72-2	100MG	₹8421.85	2022-06-14	Buy
Sigma-Aldrich(India)	H6010	L-Homocystine ≥98% (HPLC)	626-72-2	500MG	₹18803.03	2022-06-14	Buy
Sigma-Aldrich(India)	H6010	L-Homocystine ≥98% (HPLC)	626-72-2	1G	₹32345.1	2022-06-14	Buy

Product number	Packaging	Price	Buy
H6010	100MG	₹8421.85	Buy
H6010	500MG	₹18803.03	Buy
H6010	1G	₹32345.1	Buy

L-Homocystine Chemical Properties,Uses,Production

Chemical Properties

L-homocysteine is an aliphatic amino acid with the molecular formula (C8H16N2O4S2). It is a white powder with an acidic taste and is easily soluble in water. It has limited solubility in ethanol. L-homocysteine has a sulfhydryl group on its side chain, which allows it to form disulfide bonds with other L-homocysteine residues in proteins. This feature contributes to the stable three-dimensional structure of proteins. As a result, L-homocysteine finds extensive applications in industries such as pharmaceuticals, food, feed, and cosmetics.

Uses

Increased levels lead to hyperhomocysteinemia; a cardiovascular risk factor in prediction of coronary heart disease as well as being associated with congenital birth defects, pregnancy complications and cancer.

Synthesis

L-homoserine(626-72-2) is biosynthesized from L-aspartate, which is synthesized from oxaloacetate, a TCA cycle intermediate. Homoserine is activated through esterification to form the O-acetyl ester by the enzyme homoserine O-acetyltransferase. In certain organisms, including the yeast Saccharomyces cerevisiae and certain bacteria, hydrogen sulfide reacts with O-acetyl-L-homoserine, replacing the acetyl group and forming L-homocysteine.
L-homocysteine biosynthesis

Purification Methods

The acid (3g) is dissolved in freshly boiled H2O (30mL) under N2, cooled under N2 (all operations should be under N2), absolute EtOH (100mL) is added, the acid is filtered off, and a second crop is obtained by diluting the filtrate to 500mL with absolute EtOH, kept overnight in a refrigerator, filtered, washed with EtOH and dried in a vacuum. The D(R,R)-form has similar properties but is –ve in M HCl and +ve in H2O. [du Vigneaud & Patterson J Biol Chem 109 101 1935, du Vigneaud & Brown Biochemical Preparations 5 93, 95 1975, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2667-2670 1961, Beilstein 4 III 1643, 4 IV 3199, Koegel et al. J Am Chem Soc 77 5708 1955.]

L-Homocystine Preparation Products And Raw materials

Raw materials

L-Homoserine L-aspartic acid, sodium salt (S)-4-ACETOXY-2-AMINO-BUTYRIC ACID homoserine O-acetyltransferase Hydrogen Sulfide

RIBOMINUS(BACTERIA)

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Preparation Products

L-Homocystine Suppliers

Global( 244)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	China	2503	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32836	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29888	58	Inquiry
Accela ChemBio Inc.	+1-858-6993322	United States	19479	58	Inquiry
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	China	2995	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
Henan Bao Enluo International TradeCo.，LTD	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Xi'an Kono chem co., Ltd.,	58
Chongqing Chemdad Co., Ltd	58

L-Homocystine Spectrum

L-Homocystine(626-72-2)MS L-Homocystine(626-72-2)IR1 L-Homocystine(626-72-2)IR2

626-72-2(L-Homocystine)Related Search:

4-Aminobutyric acid D-2-Aminobutyric acid N-Acetyl-L-cysteine DL-Homocysteine L-Cystine

DL-2-AMINOBUTYRIC ACID L-Cysteine Selenium sulfide DL-3-Aminobutyric acid Cyproterone acetate

Indole-3-butyric acid DL-2-Aminobutyric acid L(+)-2-Aminobutyric acid 3-CARBOXYPROPYL DISULFIDE Butyl disulfide

Methyl propyl disulfide r-Amino Butryric Acid ETHYL PROPYL DISULFIDE

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(2S,2'S)-2,2'-Diamino-(4,4'-dithiobisbutyric acid) 3,3'-(Dithiobismethylene)bisalanine 4,4'-Dithiobis[(2S)-2-aminobutanoic acid] 4,4'-Dithiobis[(S)-2-aminobutanoic acid] 4,4'-Dithiobis[(S)-2-aminobutyric acid] (2S,2'S)-4,4'-Dithiobis[2-aMinobutanoic Acid] [S-(R*,R*)]-4,4'-Dithiobis[2-aMinobutanoic Acid] L-Homocystine ,99% L-Homocystine,L-4,4′-Dithiobis(2-aminobutanoic acid) L-HOMOCYSTINE, >=98% (HPLC) (H-L-HomoCys-OH)2 L-Homocystine≥ 99% (Assay) H-HoCys-OH L-4,4'-Dithiobis(2-aminobutanoic acid) (H-HCY-OH)2 (H-HOCYS-OH)2 (H-HOMOCYS-OH)2 H-L-HOCYSTINE L-4,4'-DITHIO-BIS(2-AMINOBUTANOIC ACID) 4,4’-dithiobis[2-amino-,[s-(theta,theta)]-butanoicaci (H-Hcy-OH)? L-homocystine cell culture tested [S-(R*,R*)]-4,4'-dithiobis[2-aminobutyric] acid 2-amino-4-(3-amino-3-carboxy-propyl)disulfanyl-butanoic acid H-HoCys-OH (H-Hcys-OH) 2 L-Homocystine H-L-HCystine L-Homocystine USP/EP/BP Butanoic acid, 4,4'-dithiobis[2-amino-, (2S,2'S)- (2S)-2-amino-4-{[(3S)-3-amino-3-carboxypropyl]disulfanyl}butanoic acid (2S,2'S)-4,4'-Disulfanediylbis(2-aMinobutanoic acid) L Homocystine,Inhibitor,Endogenous Metabolite,LHomocystine,inhibit,L-Homocystine Vincamine Impurity 1( Vincamine EP Impurity A ) L-Homocystine 626-72-2 C8H16N2O4S2 Unnatural Amino Acid Derivatives Specialty Synthesis Peptide Synthesis Homo-Amino Acids Amines Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds Amino Acids