MIDECAMYCIN
- CAS No.
- 35457-80-8
- Chemical Name:
- MIDECAMYCIN
- Synonyms
- medemycin;mydecamycin;medecamycin;sf837;Aboren;Myoxam;Midecin;Momicin;Macropen;MoMicine
- CBNumber:
- CB5175530
- Molecular Formula:
- C41H67NO15
- Molecular Weight:
- 813.97
- MOL File:
- 35457-80-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/16 16:33:45
| Melting point | 155℃ -156℃ |
|---|---|
| Boiling point | 874℃ |
| alpha | D23 -67° (c = 1 in ethanol) |
| Density | 1.1651 (rough estimate) |
| refractive index | 1.6220 (estimate) |
| Flash point | >110°(230°F) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.9 in 50% aq ethanol |
| color | White to Off-White |
| Water Solubility | Soluble in methanol or ethanol. Insoluble in water |
MIDECAMYCIN Chemical Properties,Uses,Production
Description
Midecamycin, a macrolide antibiotic having a 16-membered lactone ring, was found in the culture broth of Streptomyces mycarofaciens by Meiji Seika Kaisha in 1971. Under specific culture conditions, it is produced by the organism as a single component. Midecamycin shows almost the same antimicrobial spectrum and activity as kitasamycin. Although its serum and urine concentrations are low, it distributes in tissues at high concentration following oral administration.
Chemical Properties
White Solid
Uses
A 16-membered ring macrolide antibiotic used in ophthalmology as well as other medical fields.
Pharmaceutical Applications
A naturally occurring metabolite of Streptomyces mycarofaciens, supplied as the native compound and as midecamycin acetate for oral administration.
It is rapidly and extensively metabolized and is said to exhibit less toxicity than earlier macrolides. It is of limited availability.
MIDECAMYCIN Preparation Products And Raw materials
Global( 137)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 | China | 246 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | CHINA | 9427 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
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propanoic acid [(11Z,13E)-6-[[(2S,3R,4R,5S,6R)-4-(dimethylamino)-3-hydroxy-5-[[(2S,4R,5R,6R)-4-hydroxy-4,6-dimethyl-5-(1-oxopropoxy)-2-oxanyl]oxy]-6-methyl-2-oxanyl]oxy]-10-hydroxy-5-methoxy-9,16-dime
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(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-4-(Dimethylamino)-3-hydroxy-5-(((2S,4R,5S,6S)-4-hydroxy-4,6-dimethyl-5-(propionyloxy)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-ox
(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-4-(Dimethylamino)-3-hydroxy-5-(((2S,4R,5S,6S)-4-hydroxy-4,6-dimethyl-5-(propionyloxy)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl propionate
(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-4-(dimethylamino)-5-hydroxy-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-(propanoyloxy)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl propanoate
Midecamycin (>85%)
MIDECAMYCIN USP/EP/BP
DMUAPQTXSSNEDD-BJXZGPOLSA-N
medemycin
mydecamycin
medecamycin
35457-80-8
3557-80-8
C41H67NO15
Pharmaceuticals
Carbohydrates & Derivatives
Chiral Reagents
Intermediates & Fine Chemicals