(+)-BORNEOL
- CAS No.
- 464-43-7
- Chemical Name:
- (+)-BORNEOL
- Synonyms
- (1R,2S,4R)-borneol;(+)-Borneol;Borneol（Chp);D-(+)-BORNEOL;Asparagus Root;dextro-borneol;(+)-BORNEOL 98%;(+)-Borneol 97%;d-Bornyl alcohol;(1R)-endo-Borneol
- CBNumber:
- CB5184253
- Molecular Formula:
- C10H18O
- Molecular Weight:
- 154.25
- MOL File:
- 464-43-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/6 15:55:11
| Melting point | 206-209 °C (lit.) |
|---|---|
| alpha | 36 º (C=5 IN ETOH) |
| Boiling point | 237.64°C (rough estimate) |
| Density | 0.8704 (rough estimate) |
| refractive index | 1.4723 (estimate) |
| FEMA | 2157 | BORNEOL |
| Flash point | 150 °F |
| storage temp. | 2-8°C |
| solubility | DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 16 mg/ml; Ethanol: 16 mg/ml |
| pka | 15.36±0.60(Predicted) |
| Odor | at 10.00 % in dipropylene glycol. pine camphor earthy |
| Odor Type | balsamic |
| optical activity | [α]20/D 37.0±2.0°, c = 5 in ethanol |
| Water Solubility | 0.74g/L(25 ºC) |
| BRN | 2038056 |
| LogP | 2.850 |
| CAS DataBase Reference | 464-43-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H228 | |||||||||
| Precautionary statements | P210 | |||||||||
| Hazard Codes | F,Xn | |||||||||
| Risk Statements | 11-20/21/22 | |||||||||
| Safety Statements | 16-33-36-7/9 | |||||||||
| RIDADR | UN 1312 4.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | ED7060000 | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
(+)-BORNEOL price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | CRM40901 | (+)-Borneol solution certified reference material, 2000?μg/mL in methanol, ampule of 1?mL | 464-43-7 | 1ML | ₹12262.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 68878 | (+)-Borneol analytical standard | 464-43-7 | 10MG | ₹19480 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 420247 | (+)-Borneol 97% | 464-43-7 | 1G | ₹11360 | 2022-06-14 | Buy |
(+)-BORNEOL Chemical Properties,Uses,Production
Chemical Properties
Almost insoluble in water, poorly soluble in Propylene glycol, very soluble in alcohol, miscible with most perfume oils. Dry-camphoraceous, woody-peppery odor. The dryness is characteristic and constitutes the main difference from the odor of isoBorneol. The odor of Borneol is often compared to that of a good grade Rosemary oil (in which Borneol is present).
Uses
(+)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).
Application
(+)-Borneol has a woody, somewhat minty and slightly burning taste. This alcohol blends excellently with Olibanum products for “incense” type fragrances, and it forms a good background in many herbaceous-camphoraceous fragrances, Lavender- and Citrus cologne types, many tyDes of Room-freshener fragrance, Pine odors, etc.
General Description
(+)-Borneol, a bicyclic monoterpene, is found in the essential oils of medicinal plants and is commonly used in traditional Chinese medicine for analgesia and anaesthesia.
Anticancer Research
Wild asparagus root is known as “tian men dong” in traditional Chinese medicine. Itis used to relieve asthma, suppress coughing, and promote expectoration (Huang1998). It is held to be sweet and bitter in flavour and cold in nature, nourishing thelungs and moistening dryness (McNamara and Song 1995). Though studies conductedon asparagus root to examine its biological effects have only been conductedon animals, the evidence so far shows anticancer activity against leukaemia and lungcancer by means of the inhibition of tumour necrosis factor alpha (Huang et al. 2008).
Purification Methods
It can be steam distilled, the distillate is extracted into Et2O, the extract dried with Drierite and evaporated. The residue is then recrystallised from boiling EtOH (charcoal) or pet ether. [Clark & Read J Chem Soc 1773 1934, Beilstein 6 III 295, 6 IV 281.]
(+)-BORNEOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21677 | 55 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26415 | 58 | Inquiry |
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