ChemicalBook > Product Catalog >Biochemical Engineering >Condensing agent >N-Hydroxy-5-norbornene-2,3-dicarboximide
N-Hydroxy-5-norbornene-2,3-dicarboximide
- CAS No.
- 21715-90-2
- Chemical Name:
- N-Hydroxy-5-norbornene-2,3-dicarboximide
- Synonyms
- HONB;N-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ACID IMIDE;2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-Methanoisoindole-1,3(2H)-dione;N-Hydroxy-5-norborne;LABOTEST-BB LT00112336;Endo-N-Hydroxy-5-Norbornene-2,;N-Hydroxynorborna-5-ene-2,3-dicarbimide;N-Hydroxy-5-Norborene-2,3-Dicarboximide;N-HYDROXY-5-NORBORNENE-2,3-DICARBOXIMIDE;N-hydroxynorborn-5-ene-2,3-dicarboximide
- CBNumber:
- CB9121858
- Molecular Formula:
- C9H9NO3
- Molecular Weight:
- 179.17
- MOL File:
- 21715-90-2.mol
- Modify Date:
- 2023/4/23 13:52:06
| Melting point | 165-170 °C (lit.) |
|---|---|
| Boiling point | 311.69°C (rough estimate) |
| Density | 1.2822 (rough estimate) |
| refractive index | 1.5600 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Soluble in ethanol |
| form | Solid |
| pka | 9.00±0.20(Predicted) |
| color | Off-White |
| BRN | 13540 |
| CAS DataBase Reference | 21715-90-2(CAS DataBase Reference) |
| EPA Substance Registry System | 4,7-Methano-1H-isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-hydroxy- (21715-90-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29280090 | |||||||||
| NFPA 704 |
|
N-Hydroxy-5-norbornene-2,3-dicarboximide price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 226378 | N-Hydroxy-5-norbornene-2,3-dicarboxylic acid imide 97% | 21715-90-2 | 50G | ₹8075.45 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H0528 | N-Hydroxy-5-norbornene-2,3-dicarboximide [for Peptide Synthesis] | 21715-90-2 | 25G | ₹3500 | 2022-05-26 | Buy |
| ALFA India | ALF-A13205-30 | endo-N-Hydroxy-5-norbornene-2,3-dicarboximide, 97% | 21715-90-2 | 250g | ₹19771 | 2022-05-26 | Buy |
| ALFA India | ALF-A13205-18 | endo-N-Hydroxy-5-norbornene-2,3-dicarboximide, 97% | 21715-90-2 | 50g | ₹6068 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0528 | N-Hydroxy-5-norbornene-2,3-dicarboximide [for Peptide Synthesis] | 21715-90-2 | 250G | ₹13800 | 2022-05-26 | Buy |
N-Hydroxy-5-norbornene-2,3-dicarboximide Chemical Properties,Uses,Production
Description
N-Hydroxy-5-norbornene-2,3-dicarboximide (NHD) is a compound that has antiviral activity and is used to treat HIV infections. It inhibits the reverse transcriptase enzyme in the virus, which blocks the synthesis of viral DNA. The ferroelectric properties of NHD were first observed by observing changes in its melting point when mixed with water. This property makes it useful for diagnosis purposes. In animal studies, a dose of 5 mg/kg was found to be effective against cancer cells and the drug showed no toxicity in humans at doses up to 500 mg/day. The optimal reaction conditions for NHD are pH 6 and temperature 45 degrees Celsius.
Chemical Properties
white to off-white crystalline powder
Uses
N-Hydroxy-5-norbornene-2,3-dicarboximide(HONB) is used in solution-phase peptide synthesis. Used in the synthesis of enkephalin analogs.
Purification Methods
Dissolve the imide in CHCl3, filter, evaporate and recrystallise from EtOAc. IR (nujol): max 1695, 1710 and 1770 (C=O), and 3100 (OH) cm-1. The O-acetyl derivative has m 113-114o (from EtOH) with IR bands at max 1730, 1770 and 1815 cm-1 only, and the O-benzoyl derivative has m 143-144o (from propan-2-ol or *C6H6). [Bauer & Miarka J Org Chem 24 1293 1959, Fujino et al. Chem Pharm Bull Jpn 22 1857 1974]. [Beilstein 21/10 V 188.]
N-Hydroxy-5-norbornene-2,3-dicarboximide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 271)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Nanjing Triumpharm Co.,Ltd | +86-02586182925 +86-15105172550 | China | 129 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16216 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21670 | 55 | Inquiry |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | China | 1011 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
N-Hydroxy-5-norbornene-2,3-dicarboximide Spectrum
N-Hydroxy-5-norbornene-2,3-dicarboximide(21715-90-2)MSN-Hydroxy-5-norbornene-2,3-dicarboximide(21715-90-2)1HNMRN-Hydroxy-5-norbornene-2,3-dicarboximide(21715-90-2)13CNMRN-Hydroxy-5-norbornene-2,3-dicarboximide(21715-90-2)IR1N-Hydroxy-5-norbornene-2,3-dicarboximide(21715-90-2)IR2N-Hydroxy-5-norbornene-2,3-dicarboximide(21715-90-2)Raman
21715-90-2(N-Hydroxy-5-norbornene-2,3-dicarboximide)Related Search:
N-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIMIDE
N-HYDROXY-5-NORBORNENE-2,3-DICARBOXIMIDE
N-HYDROXYBICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLIC ACID IMIDE
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LABOTEST-BB LT00112336
3(2h)-dione,3a,4,7,7a-tetrahydro-2-hydroxy-7-methano-1h-isoindole-1
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N-Hydroxy-5-norborne
N-Hydroxy-5-norbornene-endo-2,3-dicarboximide97%
N-Hydroxy-5-norbornene-2,3-dicarboxylic acid imide 97%
N-Hydroxy-5-norbornene-2.3-dicarboxylic imide
endo-N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarbo
Honb(N-Hydrozy-5-Norbornene-2.3-DicarboxylicImide)
N-Hydroxy-5-Norborene-2,3-Dicarboximide
N-Hydroxy-5-norbornene-2,3-dicarboximide, 99+%
Endo-N-Hydroxy-5-Norbornene-2,
HONB N-Hydroxy-5-norbornene-endo-2,3-dicarboximide N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid imide
HONB, endo-N-Hydroxy-5-norbornene-2,3-dicarboximide
ENDO-N-HYDROXY-5-NORBORNENE-2,3-DICARBOXIMIDE HONB
HONB N-HYDROXY-5-NORBORNENE-2.3-DICARBOXYLIMIDE
N-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ACID IMIDE (HONB)
N-hydroxynorborn-5-ene-2,3-dicarboximide
N-Hydroxy-5-norbornene- 2,3-dicarboxylicacid imide,endo-N-Hydroxy-5- norbornene-2,3-dicarboximide
N-HYDROXY-5-NORBORNENE-2,3-DICARBOXIMIDE (HONB)
N-HYDROXY-5-NORBONENE-2,3-DICARBOXYLIC IMIDE
N-Hydroxy-5-norbornene-2,3-dicarboximide [for Peptide Synthesis]
N-Hydroxy-5-norbornene-2,3-dicarboximide USP/EP/BP
TIANFU-CHEM 21715-90-2 N-Hydroxy-5-norbornene-2,3-dicarboximide
4-hydroxy-4-azatricyclo[5.2.1.02,]dec-8-ene-3,5-dione
N-Hydroxy-5-norbornene-2,4-dicarboximide
N-hydroxy-5-norbornene-2.3-dicarboxylimide(HONB)
N-Hydroxy-5-norbornene-2,3-dicarboximide[forPeptideSynthesis]>
N-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ACID IMIDE
HONB
2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-Methanoisoindole-1,3(2H)-dione
N-Hydroxy-5-Norbornene-2,3-dimethylimide
21715-90-2
5C9H9NO3
Synthetic Reagents
Coupling
Coupling Reactions (Peptide Synthesis)
Peptide Synthesis
Condensation & Active Esterification
Active Esters/Additives
Coupling Reagent
Medical Intermediates
Biochemistry
Condensation & Active Esterification
Coupling Reactions (Peptide Synthesis)
Peptide Synthesis
Synthetic Organic Chemistry