ChemicalBook > Product Catalog >Biochemical Engineering >nucleic acid drugs >1-METHYLADENOSINE

1-METHYLADENOSINE

1-METHYLADENOSINE Structure
CAS No.
15763-06-1
Chemical Name:
1-METHYLADENOSINE
Synonyms
N1-Me-rA;N1-Me-Adenosine;1-METHYLADENOSINE;Adenosine, 1-methyl-;1-methyladenosine free base;N,6-Didehydro-1,6-dihydro-1-methyladenosine;(2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol;inhibit,1-Methyladenosine,1 Methyladenosine,Endogenous Metabolite,Inhibitor,1Methyladenosine;(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CBNumber:
CB5187128
Molecular Formula:
C11H15N5O4
Molecular Weight:
281.27
MOL File:
15763-06-1.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:03

1-METHYLADENOSINE Properties

Melting point >217°C (dec.)
Boiling point 655.4±65.0 °C(Predicted)
Density 1.88±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO (Slightly), Water (Slightly, Sonicated)
form Solid
pka 13.24±0.70(Predicted)
color White to Off-White
Stability Hygroscopic, Light Sensitive

SAFETY

Risk and Safety Statements

Safety Statements  24/25
HS Code  29389090

1-METHYLADENOSINE Chemical Properties,Uses,Production

Description

1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.

Chemical Properties

White to off-white crystalline powder

Uses

1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.

Definition

ChEBI: A methyladenosine carrying a methyl substituent at position 1.

1-METHYLADENOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

1-METHYLADENOSINE Suppliers

Global( 90)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Gagri Global IT Services Pvt. Ltd. +91-40-27170174, Telangana, India 1321 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10318 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13127 58 Inquiry
NewCan Biotech Limited +86-0571-86912261 +8613735419629 China 9980 58 Inquiry
N,6-Didehydro-1,6-dihydro-1-methyladenosine 1-METHYLADENOSINE 1-methyladenosine free base (2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol (2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol Adenosine, 1-methyl- N1-Me-Adenosine N1-Me-rA inhibit,1-Methyladenosine,1 Methyladenosine,Endogenous Metabolite,Inhibitor,1Methyladenosine (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3,4-diol 15763-06-1 Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs Biochemicals and Reagents BioChemical Biochemicals and Reagents Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides