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ISOXSUPRINE HYDROCHLORIDE

ISOXSUPRINE HYDROCHLORIDE Structure
CAS No.
579-56-6
Chemical Name:
ISOXSUPRINE HYDROCHLORIDE
Synonyms
Navilox;isolait;Dilavase;vasoplex;Vasotran;Duvadilan;Divadilan;vasodilan;Vadosilan;suprilent
CBNumber:
CB5197363
Molecular Formula:
C18H24ClNO3
Molecular Weight:
337.84
MOL File:
579-56-6.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:11

ISOXSUPRINE HYDROCHLORIDE Properties

Melting point 203-204°
storage temp. Inert atmosphere,2-8°C
solubility Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in methylene chloride.
pka pKa 8.0 (Uncertain);9.8 (Uncertain)
form Solid
color White to off-white
CAS DataBase Reference 579-56-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H410
Precautionary statements  P264-P270-P273-P301+P312-P391-P501
Hazard Codes  Xn,N
Risk Statements  22-50/53-63-50
Safety Statements  36-61-60
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  DO8225000
HS Code  2922504500
Toxicity LD50 in rats (mg/kg): 1750 orally; 164 i.p. (Goldenthal)
NFPA 704
0
1 0

ISOXSUPRINE HYDROCHLORIDE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR3190 Isoxsuprine Hydrochloride pharmaceutical secondary standard, certified reference material 579-56-6 500MG ₹18380.85 2022-06-14 Buy
Sigma-Aldrich(India) I0880 Isoxsuprine hydrochloride analytical standard 579-56-6 5G ₹5834.68 2022-06-14 Buy
Product number Packaging Price Buy
PHR3190 500MG ₹18380.85 Buy
I0880 5G ₹5834.68 Buy

ISOXSUPRINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Isoxsuprine is an adrenergic receptor modulator that has α-adrenergic receptor (α-AR) antagonist and β-AR agonist properties. It induces vasodilation of isolated equine common digital artery strips precontracted with norepinephrine, indicating an α-AR effect, and induces relaxation of isolated fowl cecum, an effect that can be blocked by the β-AR antagonist propranolol (Item Nos. 23349 | 17291). Isoxsuprine has antinociceptive effects in an acetic acid writhing test in mice. It also inhibits oxytocin-induced contractions in isolated rat uterus (IC50 = 9.15 μM). It delays labor onset in rats by 31.63 hours when administered at a dose of 10 mg/kg per day on days 13 to 21 of gestation but increases heart rate with increasing concentration.

Chemical Properties

White Solid

Uses

As a vasilodator drug, Isoxsuprine Hydrochloride is used in veterinary medicine for the treatment of navicular syndrome and laminitis in horses. Isoxsuprine Hydrochloride has been shown to be a β-adrenoreceptor antagonist with β-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. Studies suggest that Isoxsuprine Hydrochloride may be useful as a as a tocolytic agent in the treatment of preterm labour.

ISOXSUPRINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 123)Suppliers
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OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
Medilink Pharmachem +91 (79) 3007-0133 New Delhi, India 424 50 Inquiry
GANGWAL CHEMICALS PVT LTD +91 22 28889000 New Delhi, India 75 58 Inquiry
vasodilan vasoplex Isoxsuprine 4-Hydroxy-α-[1-[(1-Methyl-2-phenoxyethyl)aMino]ethyl]benzeneMethanol Hydrochloride Benzenemethanol, 4-hydroxy-.alpha.-1-(1-methyl-2-phenoxyethyl)aminoethyl-, hydrochloride 1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1 hydrochloride Benzenemethanol, 4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (9CI) Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI) Dilavase Divadilan Duvadilan Duviculine Navilox Norephedrine, p-hydroxy-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (6CI) Vadosilan Vasotran Aids196186 Aids-196186 Vasodilian Vasosurpine Isoxsuprine Hydrochloride (200 mg) ISOXSUPRINE HCL ISOXSUPRINE HYDROCHLORIDE 1-(p-hydroxyphenyl)-2-(1’-methyl-2’-phenoxy)ethylaminopropanol-1hydrochlorid 2-(3-phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanolhydrochloride isolait isoxsuprinhydrochloride p-hydroxy-alpha-(1-((1-methyl-2-phenoxyethyl)amino)ethyl)-benzylalcohohyd suprilent p-Hydroxy-N-(1-Methyl-2-phenoxyethyl)norephedrine Hydrochlorid p-Hydroxy-α-[1-[(1-Methyl-2-phenoxyethyl)aMino]ethyl]benzyl Alcohol Hydrochloride erythro-Isoxsuprine hydrochloride BenzeneMethanol,4-hydroxy-a-[1-[(1-Methyl-2-phenoxyethyl)aMino]ethyl]-,hydrochloride (1:1) Isoxsuprine hydrochloride Solution, 100ppm (1RS,2SR)-1-(4-Hydroxyphenyl)-2-[(1SR)1-methyl-2-phenoxyethylamino]propan-1-ol hydrochloride (1RS,2SR,1′SR)-1-(p-Hydroxyphenyl)-2-(1′-methyl-2′-phenoxyethylamino)-1-propanol hydrochloride, mixture of enantiomers Isoxsuprine hydrochloride CRS 4-(1-Hydroxy-2-((1-phenoxypropan-2-yl)amino)propyl)phenol hydrochloride Isoxsuprine HydrochlorideQ: What is Isoxsuprine Hydrochloride Q: What is the CAS Number of Isoxsuprine Hydrochloride Q: What is the storage condition of Isoxsuprine Hydrochloride Q: What are the applications of Isoxsuprine Hydrochloride TIANFUCHEM--High purity ISOXSUPRINE HYDROCHLORIDE factory price Isoxsuprine Hydrochloride (1354003) IsoShupulin hydrochloride Paracetamol Impurity 24-d3 579-56-6 597-56-6 C18H23NO3ClH Analytical Standards Analytical Chromatography Product Catalog Alphabetic Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals VASODILAN