LY 367385
- CAS No.
- 198419-91-9
- Chemical Name:
- LY 367385
- Synonyms
- LY 367385;(±)-LY367385;LY367385,LY-367385;LY-367385 hydrochloride;SGIKDIUCJAUSRD-QMMMGPOBSA-N;LY 367385, mGlu1a antagonist;(S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid;4-[(R)-amino(carboxy)methyl]-3-methylbenzoic acid;4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid;(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid
- CBNumber:
- CB5200038
- Molecular Formula:
- C10H11NO4
- Molecular Weight:
- 209.2
- MOL File:
- 198419-91-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
LY 367385 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | L4420 | LY-367385 hydrochloride ≥98% (HPLC) | 198419-91-9 | 5MG | ₹8746.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L4420 | LY-367385 hydrochloride ≥98% (HPLC) | 198419-91-9 | 25MG | ₹32929.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 5.04658 | LY 367385 Hydrochloride - CAS 198419-91-9 (fr - Calbiochem | 198419-91-9 | 5MG | ₹12440 | 2022-06-14 | Buy |
LY 367385 Chemical Properties,Uses,Production
Uses
LY 367385 is a selective mGlu1a receptor antagonist used to treat inflammatory diseases (ie. multiple sclerosis) and neurodegenerative diseases (ie. Alzheimer’s) (1,2).
Biological Activity
A selective mGlu 1a receptor antagonist, with an IC 50 value of 8.8 μ M for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μ M for mGlu 5a , and negligible action on group II and III receptors. Also available as part of the Group I mGlu Receptor Tocriset™ .
Biochem/physiol Actions
LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).
LY 367385 Preparation Products And Raw materials
Raw materials
Preparation Products
LY 367385 Suppliers
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32202 | 58 | Inquiry |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8467 | 58 | Inquiry |
| Aladdin Scientific | United States | 52924 | 58 | Inquiry | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +8617705817739 | China | 53881 | 58 | Inquiry |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | China | 233051 | 58 | Inquiry |
| BEIJING ECHIRAL MED TECH DVLP | 18010053931 | China | 8298 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 4008200310 | China | 24683 | 58 | Inquiry |
| BOC Sciences | USA | 0 | 65 | Inquiry | |
| DC Chemicals | 021-58447131 13564518121 | China | 9409 | 58 | Inquiry |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-81148696 18161915376 | China | 9799 | 58 | Inquiry |
198419-91-9(LY 367385)Related Search:
N,N-DIETHYLBENZAMIDE
(+)-MCPG, LY367385, S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid
(S)-AMINO-O-TOLYL-ACETIC ACID
Benzenemethanol, 4-[(1R)-1-aminoethyl]-
AMINO-(2,4-DIMETHYL-PHENYL)-ACETIC ACID
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(S)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
LY 367385
(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid
(S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid
(S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid
LY-367385 hydrochloride
(R)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneacetic acid
LY-367385;(R)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid
Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
SGIKDIUCJAUSRD-QMMMGPOBSA-N
LY367385,LY-367385
4-[(R)-amino(carboxy)methyl]-3-methylbenzoic acid
4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid
LY 367385, mGlu1a antagonist
(±)-LY367385
198419-91-9
Glutamate