LY 367385

LY 367385 Structure
CAS No.
198419-91-9
Chemical Name:
LY 367385
Synonyms
LY 367385;LY367385,LY-367385;LY-367385 hydrochloride;SGIKDIUCJAUSRD-QMMMGPOBSA-N;(S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid;(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid;(S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid;(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid;Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-;Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
CBNumber:
CB5200038
Molecular Formula:
C10H11NO4
Molecular Weight:
209.2
MOL File:
198419-91-9.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

LY 367385 Properties

storage temp. Desiccate at RT
solubility H2O: >10mg/mL
form powder
color white to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

LY 367385 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) L4420 LY-367385 hydrochloride ≥98% (HPLC) 198419-91-9 5MG ₹8746.6 2022-06-14 Buy
Sigma-Aldrich(India) L4420 LY-367385 hydrochloride ≥98% (HPLC) 198419-91-9 25MG ₹32929.65 2022-06-14 Buy
Sigma-Aldrich(India) 5.04658 LY 367385 Hydrochloride - CAS 198419-91-9 (fr - Calbiochem 198419-91-9 5MG ₹12440 2022-06-14 Buy
Product number Packaging Price Buy
L4420 5MG ₹8746.6 Buy
L4420 25MG ₹32929.65 Buy
5.04658 5MG ₹12440 Buy

LY 367385 Chemical Properties,Uses,Production

Uses

LY 367385 is a selective mGlu1a receptor antagonist used to treat inflammatory diseases (ie. multiple sclerosis) and neurodegenerative diseases (ie. Alzheimer’s) (1,2).

Biological Activity

A selective mGlu 1a receptor antagonist, with an IC 50 value of 8.8 μ M for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μ M for mGlu 5a , and negligible action on group II and III receptors. Also available as part of the Group I mGlu Receptor Tocriset™ .

Biochem/physiol Actions

LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).

LY 367385 Preparation Products And Raw materials

Raw materials

Preparation Products

LY 367385 Suppliers

Global( 49)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
Tianjin Xinkangyou Biotechnology Co., LTD 19922659386 China 2426 58 Inquiry
BOC Sciences USA 0 65 Inquiry
DC Chemicals 021-58447131 13564518121 China 9412 58 Inquiry
LABTER SCIENTIFIC CO.,LTD 010-56330744 15210344275 China 10000 58 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 17691182729 18161915376 China 10011 58 Inquiry
Nacalai Tesque, Inc. 81 75 251 1723 Japan 6048 75 Inquiry
(S)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID LY 367385 (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid (S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid (S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid LY-367385 hydrochloride (R)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneacetic acid LY-367385;(R)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)- SGIKDIUCJAUSRD-QMMMGPOBSA-N LY367385,LY-367385 Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)- 198419-91-9 Glutamate