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Prasugrel Hydrochloride

Prasugrel Hydrochloride Structure
CAS No.
389574-19-0
Chemical Name:
Prasugrel Hydrochloride
Synonyms
Prasugrel HCl;Prasugrenhydrochloride;2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride;Ridomil 72WP;Prasugrel HCI;Unii-G89jq59I13;Effient Hydrochloride;Prasugrel hydrochloric;LY 640315 Hydrochloride;PRASUGREL HYDROCHLORIDE
CBNumber:
CB52465251
Molecular Formula:
C20H20FNO3S.ClH
Molecular Weight:
409.907
MOL File:
389574-19-0.mol
MSDS File:
SDS
Modify Date:
2024/5/14 10:41:42
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Prasugrel Hydrochloride Properties

Melting point >173?C (dec.)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form Solid
color White to Pale Brown
InChI InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H
InChIKey JALHGCPDPSNJNY-UHFFFAOYSA-N
SMILES N1(CCC2SC(OC(C)=O)=CC=2C1)C(C1C=CC=CC=1F)C(=O)C1CC1.Cl

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
HS Code  2934990002

Prasugrel Hydrochloride Chemical Properties,Uses,Production

Description

Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation.

Chemical Properties

White to Off-White Solid

in vivo

In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM. Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.

Prasugrel Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Prasugrel Hydrochloride Suppliers

Global( 274)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Saptagir Laboratories PVT.LTD. +91-9059978049 +91-9059978049 Telangana, India 31 58 Inquiry
SGMR PHARMACEUTICALS PVT LTD +91-9032001889 +91-9032001889 Telangana, India 83 58 Inquiry
Dodhia Group +91-9619867345 +91-9619867345 Mumbai, India 129 58 Inquiry
Lupin Ltd +91-8019896181 +91-8019896181 Maharashtra, India 93 58 Inquiry
Alembic Pharmaceuticals Limited +91-2652280880 +91-2652280550 Gujarat, India 115 58 Inquiry
Lee Pharma Ltd +91-9849085929 +91-9849085929 Hyderabad, India 42 58 Inquiry
Macleods Pharmaceuticals Limited +91-2266762800 +91-2266762800 Maharashtra, India 116 58 Inquiry
Hetero Drugs Limited +91-4023704923 +91-4023704923 Telangana, India 296 58 Inquiry
HRV Global Life Sciences +91-9820219686 +91-9820219686 Telangana, India 379 58 Inquiry
KARPSCHEM LABORATORIES +91-7249203006 +91-7249203006 Maharashtra, India 786 58 Inquiry
Supplier Advantage
Saptagir Laboratories PVT.LTD. 58
SGMR PHARMACEUTICALS PVT LTD 58
Dodhia Group 58
Lupin Ltd 58
Alembic Pharmaceuticals Limited 58
Lee Pharma Ltd 58
Macleods Pharmaceuticals Limited 58
Hetero Drugs Limited 58
HRV Global Life Sciences 58
KARPSCHEM LABORATORIES 58

Prasugrel Hydrochloride Spectrum

PRASUGREL HYDROCHLORIDE(389574-19-0)MSPRASUGREL HYDROCHLORIDE(389574-19-0)1HNMR

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PRASUGREL HYDROCHLORIDE Unii-G89jq59I13 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-2H,4H,5H,6H,7H,7aH-thieno[3,2-c]pyridin-2-one Prasugrel (Discontinued) Ethanone,2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-,hydrochloride (1:1) Prasugrel hydrochloric Prasugrel hydrochloride, >=99% acetic acid [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] ester [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate,hydrochloride Effient Hydrochloride LY 640315 Hydrochloride PCR 4099 (hydrochloride) 5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride Prasugrel Hydrochloride (PCR 4099 Prasugrel HydrochlorideQ: What is Prasugrel Hydrochloride Q: What is the CAS Number of Prasugrel Hydrochloride Q: What are the applications of Prasugrel Hydrochloride TIANFU-CHEM--PRASUGREL HYDROCHLORIDE Ridomil 72WP 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride Prasugrenhydrochloride Prasugrel HCl Prasugrel Hydrochloride 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7- tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride Prasugrel HCI 389574-19-0 89574-19-0 C20H20FNO3SHCl C20H20FNO3SClH API