ChemicalBook > Product Catalog >API >Synthetic Anti-infective Drugs >Antiviral drugs >Tenofovir disoproxil fumarate
Tenofovir disoproxil fumarate
- CAS No.
- 202138-50-9
- Chemical Name:
- Tenofovir disoproxil fumarate
- Synonyms
- CS-137;Tenofovir Disproxil FuMarate;2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-oxide, (2E)-2-butenedioate;CS-112;GS-433105;GS4331-05;Aids031697;GS 4331-05;GS-4331-05;Aids-031697
- CBNumber:
- CB7946998
- Molecular Formula:
- C23H34N5O14P
- Molecular Weight:
- 635.52
- MOL File:
- 202138-50-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/30 14:17:11
| Melting point | 113-115°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | powder |
| color | white to beige |
| CAS DataBase Reference | 202138-50-9(CAS DataBase Reference) |
Tenofovir disoproxil fumarate price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1794 | Tenofovir disoproxil fumarate ≥98% (HPLC) | 202138-50-9 | 10MG | ₹11355.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1794 | Tenofovir disoproxil fumarate ≥98% (HPLC) | 202138-50-9 | 50MG | ₹45698.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1957 | Tenofovir disoproxil fumarate Pharmaceutical Secondary Standard; Certified Reference Material | 202138-50-9 | 500MG | ₹19863.88 | 2022-06-14 | Buy |
Tenofovir disoproxil fumarate Chemical Properties,Uses,Production
Description
Tenofovir disoproxil is a prodrug of the acyclic nucleoside phosphonate, tenofovir . Tenofovir is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase. Due to its rapid intracellular uptake, the anti-HIV activity of tenofovir disoproxil is reportedly >100-fold greater than that of the negatively charged tenofovir in a T cell line and primary blood lymphocytes.
Chemical Properties
White Solid
Uses
Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
Definition
ChEBI: A fumarate salt prepared from equimolar amounts of tenofovir disoproxil and fumaric acid. It is used in combination therapy for the treatment of HIV infection.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Tenofovir disoproxil fumarate Preparation Products And Raw materials
Global( 546)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| CDYMAX | +91-9019317788 +91-9019317788 | Bangalore, India | 28 | 58 | Inquiry |
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Styrax Pharma Pvt Ltd | +91-4048583333 +91-9848912103 | Telangana, India | 24 | 58 | Inquiry |
| Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
| Lupin Ltd | +91-8019896181 +91-8019896181 | Maharashtra, India | 93 | 58 | Inquiry |
| Cipla Ltd | +912224826000 | Maharashtra, India | 133 | 58 | Inquiry |
| Macleods Pharmaceuticals Limited | +91-2266762800 +91-2266762800 | Maharashtra, India | 116 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Shilpa Medicare Limited (SML) | +91-8532238704 +91-9320649838 | Karnataka, India | 61 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| CDYMAX | 58 |
| Gonane Pharma | 58 |
| Styrax Pharma Pvt Ltd | 58 |
| Aurobindo Pharma Limited | 58 |
| Lupin Ltd | 58 |
| Cipla Ltd | 58 |
| Macleods Pharmaceuticals Limited | 58 |
| Hetero Drugs Limited | 58 |
| Shilpa Medicare Limited (SML) | 58 |
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Tenofovir Disoproxil fumarate
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CAS 202138-50-9 Tenofovir disoproxil fumarate
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Tenofovir Disoproxil Fumarate CRS
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GS4331-05
Tenofovir Impurity 138 Fumarate
202138-50-9
14727-20-6
134678-17-6
C23H36N5O14P
C19H30N5O10PC4H4O4
Bases & Related Reagents
Intermediates & Fine Chemicals
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