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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Tenofovir disoproxil fumarate

Tenofovir disoproxil fumarate

Tenofovir disoproxil fumarate Structure
  • ₹11355.3 - ₹45698.7
  • Product name: Tenofovir disoproxil fumarate
  • CAS: 202138-50-9
  • MF: C23H34N5O14P
  • MW: 635.52
  • EINECS:687-766-5
  • MDL Number:MFCD08141829
  • Synonyms:2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(2,2-dimethylpropyl) ester, 5-oxide, (R)-;Aids031697;Aids-031697;Bis(neopentyloc)pmpa;Tenofovir diisoproxil fuMarate;Tenofovir dipivoxil FuMarate(TDF);Tenofovir Disoproxil Fumarate (200 mg);Tenofovir DF
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1794
  • Product descriptionTenofovir disoproxil fumarate ≥98% (HPLC)
  • Packaging10MG
  • Price₹11355.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1957
  • Product descriptionTenofovir disoproxil fumarate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹19863.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1794
  • Product descriptionTenofovir disoproxil fumarate ≥98% (HPLC)
  • Packaging50MG
  • Price₹45698.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1794 Tenofovir disoproxil fumarate ≥98% (HPLC) 10MG ₹11355.3 2022-06-14 Buy
Sigma-Aldrich(India) PHR1957 Tenofovir disoproxil fumarate Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹19863.88 2022-06-14 Buy
Sigma-Aldrich(India) SML1794 Tenofovir disoproxil fumarate ≥98% (HPLC) 50MG ₹45698.7 2022-06-14 Buy

Properties

Melting point :113-115°C
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
color :white to beige
CAS DataBase Reference :202138-50-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P501 Dispose of contents/container to..…

Description

Tenofovir disoproxil is a prodrug of the acyclic nucleoside phosphonate, tenofovir . Tenofovir is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase. Due to its rapid intracellular uptake, the anti-HIV activity of tenofovir disoproxil is reportedly >100-fold greater than that of the negatively charged tenofovir in a T cell line and primary blood lymphocytes.

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Suppliers and manufacturers

Jigs Chemical ltd CDYMAX Gonane Pharma Styrax Pharma Pvt Ltd Aurobindo Pharma Limited Lupin Ltd Cipla Ltd Macleods Pharmaceuticals Limited Hetero Drugs Limited Shilpa Medicare Limited (SML)