5-Methoxyindole-3-acetonitrile

5-Methoxyindole-3-acetonitrile Structure
CAS No.
2436-17-1
Chemical Name:
5-Methoxyindole-3-acetonitrile
Synonyms
5-Methoxyindol-3-acetonitril;5-METHOXYINDOLE-3-ACETONITRILE;3-(Cyanomethyl)-5-methoxyindole;5-METHOXY-3-INDOLYLACETONITRILE;5-METHOXY-3-INDOLYLACETONITRILE 97%;3-(Cyanomethyl)-5-methoxy-1H-indole;5-Methoxy indol - 3 -yl Acetonitrile;1H-Indole-3-acetonitrile, 5-methoxy-;(5-METHOXY-1H-INDOL-3-YL)ACETONITRILE;2-(5-Methoxy-1H-indol-3-yl)acetonitrile
CBNumber:
CB5252310
Molecular Formula:
C11H10N2O
Molecular Weight:
186.21
MOL File:
2436-17-1.mol
Modify Date:
2023/4/23 13:52:06

5-Methoxyindole-3-acetonitrile Properties

Melting point 65-69 °C (lit.)
Boiling point 175-177 °C(Press: 0.01 Torr)
Density 1.224±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 16.02±0.30(Predicted)
color Very Dark Brown
CAS DataBase Reference 2436-17-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi
WGK Germany  3
HazardClass  IRRITANT
HS Code  2933998090

5-Methoxyindole-3-acetonitrile Chemical Properties,Uses,Production

Chemical Properties

Brown powder

Uses

5-Methoxyindole-3-acetonitrile is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors.

5-Methoxyindole-3-acetonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methoxyindole-3-acetonitrile Spectrum

5-METHOXY-3-INDOLYLACETONITRILE 5-METHOXYINDOLE-3-ACETONITRILE (5-METHOXY-1H-INDOL-3-YL)ACETONITRILE 2-(5-Methoxy-1H-indol-3-yl)acetonitrile 5-METHOXY-3-INDOLYLACETONITRILE 97% 5-Methoxy indol - 3 -yl Acetonitrile 3-(Cyanomethyl)-5-methoxy-1H-indole 3-(Cyanomethyl)-5-methoxyindole 5-Methoxyindol-3-acetonitril 1H-Indole-3-acetonitrile, 5-methoxy- 2436-17-1 Building Blocks Heterocyclic Building Blocks Indoles Building Blocks Heterocyclic Building Blocks Indoles blocks Carboxes IndolesOxindoles Indoles and derivatives