Iron Chelator, Dp44mT

Iron Chelator, Dp44mT Structure
CAS No.
152095-12-0
Chemical Name:
Iron Chelator, Dp44mT
Synonyms
de44mt;Dp44mT;CS-2521;Iron Chelator;Iron Chelator, Dp44mT;Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone;2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide;2-(di(pyridin-2-yl)methylene)-N,N-imethylhydrazinecarbothioamide;2-(Di(pyridin-2-yl)methylene)-N,N-dimethylhydrazinecarbothioamide;Hydrazinecarbothioamide, 2-(di-2-pyridinylmethylene)-N,N-dimethyl-
CBNumber:
CB52524488
Molecular Formula:
C14H15N5S
Molecular Weight:
285.37
MOL File:
152095-12-0.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:48

Iron Chelator, Dp44mT Properties

storage temp. 2-8°C
solubility DMSO: ≥5mg/mL
form powder
color yellow to orange
Sensitive Light Sensitive
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may ne stored at -20°C for 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  Xn
Risk Statements  22
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HazardClass  6.1
NFPA 704
0
2 0

Iron Chelator, Dp44mT price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0186 Dp44mT ≥98% (HPLC) 152095-12-0 5MG ₹8075.45 2022-06-14 Buy
Sigma-Aldrich(India) SML0186 Dp44mT ≥98% (HPLC) 152095-12-0 25MG ₹33308.53 2022-06-14 Buy
Product number Packaging Price Buy
SML0186 5MG ₹8075.45 Buy
SML0186 25MG ₹33308.53 Buy

Iron Chelator, Dp44mT Chemical Properties,Uses,Production

Uses

Iron Chelator, Dp44mT is a cell-permeable di-2-pyridyl thiosemicarbazone (DpT) based tridentate ligand.

Biochem/physiol Actions

Dp44mT (di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone) influences lysosome integrity through copper binding. It induces reactive oxygen species (ROS) generation by redox cycling of iron complex. Dp44mT exhibits anti cancer action by attenuating Ndrg-1 (N-myc downstream regulated 1), a metastasis suppressor protein. It also alters the cyclin family of proteins (A, B, D1, D2,D3 and cyclin-dependent kinase 2) known for cell-cycle regulation. Dp44mT is known to promote apoptosis in neuroepithelioma, melanoma and breast cancer.

Iron Chelator, Dp44mT Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 92)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29824 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20293 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 5225 58 Inquiry
SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40067 58 Inquiry

Iron Chelator, Dp44mT Spectrum

Iron Chelator, Dp44mT 2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone Dp44mT de44mt CS-2521 Iron Chelator Hydrazinecarbothioamide, 2-(di-2-pyridinylmethylene)-N,N-dimethyl- 2-(Di(pyridin-2-yl)methylene)-N,N-dimethylhydrazinecarbothioamide 2-(di(pyridin-2-yl)methylene)-N,N-imethylhydrazinecarbothioamide 152095-12-0