Iron Chelator, Dp44mT
- CAS No.
- 152095-12-0
- Chemical Name:
- Iron Chelator, Dp44mT
- Synonyms
- de44mt;Dp44mT;CS-2521;Iron Chelator;Iron Chelator, Dp44mT;Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone;2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide;2-(di(pyridin-2-yl)methylene)-N,N-imethylhydrazinecarbothioamide;2-(Di(pyridin-2-yl)methylene)-N,N-dimethylhydrazinecarbothioamide;Hydrazinecarbothioamide, 2-(di-2-pyridinylmethylene)-N,N-dimethyl-
- CBNumber:
- CB52524488
- Molecular Formula:
- C14H15N5S
- Molecular Weight:
- 285.37
- MOL File:
- 152095-12-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:02:48
Iron Chelator, Dp44mT price More Price(2)
Iron Chelator, Dp44mT Chemical Properties,Uses,Production
Uses
Iron Chelator, Dp44mT is a cell-permeable di-2-pyridyl thiosemicarbazone (DpT) based tridentate ligand.
Biochem/physiol Actions
Dp44mT (di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone) influences lysosome integrity through copper binding. It induces reactive oxygen species (ROS) generation by redox cycling of iron complex. Dp44mT exhibits anti cancer action by attenuating Ndrg-1 (N-myc downstream regulated 1), a metastasis suppressor protein. It also alters the cyclin family of proteins (A, B, D1, D2,D3 and cyclin-dependent kinase 2) known for cell-cycle regulation. Dp44mT is known to promote apoptosis in neuroepithelioma, melanoma and breast cancer.
Iron Chelator, Dp44mT Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 92)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29824 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20293 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | China | 5225 | 58 | Inquiry |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | China | 40067 | 58 | Inquiry |
152095-12-0(Iron Chelator, Dp44mT)Related Search:
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Iron Chelator, Dp44mT
2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide
Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone
Dp44mT
de44mt
CS-2521
Iron Chelator
Hydrazinecarbothioamide, 2-(di-2-pyridinylmethylene)-N,N-dimethyl-
2-(Di(pyridin-2-yl)methylene)-N,N-dimethylhydrazinecarbothioamide
2-(di(pyridin-2-yl)methylene)-N,N-imethylhydrazinecarbothioamide
152095-12-0