Chinese english Japanese Germany Korea

TAK875

TAK875 Structure
CAS No.
1000413-72-8
Chemical Name:
TAK875
Synonyms
CS-54;TAK875;Fasiglifam;TAK-875,TAK875;TAK-875, >=98%;TAK875 USP/EP/BP;TAK-875(Fasiglifam);FASIGLIFAM (TAK-875);TAK-875; TAK875; TAK 875.;[(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]-3-bi...
CBNumber:
CB52534865
Molecular Formula:
C29H32O7S
Molecular Weight:
524.63
MOL File:
1000413-72-8.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:20
Request For Quotation

TAK875 Properties

Melting point 123-127°C
Boiling point 739.1±60.0 °C(Predicted)
Density 1.252
storage temp. Refrigerator
solubility Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 4.36±0.10(Predicted)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

TAK875 Chemical Properties,Uses,Production

Description

The free fatty acid receptor 1 (FFAR1; GPR40) is highly expressed in pancreatic β-cells and activated by medium and long-chain fatty acids. There is evidence of a link between FFAR1 (GPR40) and the ability of fatty acids to amplify glucose-stimulated insulin secretion, making this signaling pathway a potential target for regulating diabetes, obesity, and other metabolic disorders. TAK-875 is a selective FFAR1 (GPR40) agonist (EC50 = 26 nM) that does not exhibit activity on the related FFARs FFAR2 (GPR43) or FFAR3 (GPR41).

Uses

TAK-876 is a selective G protein-coupled receptor 40 (GPR40) agonist. TAK-876 is a novel oral medication that has been developed to improve the secretion of insulin in a glucose-dependent manner, whic h has the potential to improve the control of blood sugar levels without the risk of hypoglycemia.

TAK875 Preparation Products And Raw materials

Raw materials

Preparation Products

TAK875 Suppliers

Global( 142)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 12922 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26165 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Capot Chemical Co.,Ltd. 60
Hangzhou FandaChem Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
Zhengzhou Alfa Chemical Co.,Ltd 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58

TAK875 Spectrum

TAK875(1000413-72-8)1HNMR

1000413-72-8(TAK875)Related Search:

TAK875 Mobocertinib Tak 799 Soticlestat TAK-632
TAK-733 Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]- 6-[(7S)-7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthalenecarboxamide TAK-960
chevron_left

1of2

chevron_right
TAK875 3-Benzofuranacetic acid, 6-[[2',6'-diMethyl-4'-[3-(Methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]Methoxy]-2,3-dihydro-, (3S)- (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid TAK-875, >=98% TAK-875,TAK875 [(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]-3-biphenylyl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid (S)-2-(6-((2',6'-Dimethyl-4'-(3-(methylsulfonyl)propoxy)-[1,1'-biphenyl]-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Fasiglifam (S)-2-(6-((2',6'-Dimethyl-4'-(3-(methylsulfonyl)propoxy)-[1,1'-biphenyl]-3-yl)methoxy)-2,3-dih FASIGLIFAM (TAK-875) CS-54 TAK-875(Fasiglifam) TAK-875; TAK875; TAK 875. [(3S)-6-({3-[4-(3-methanesulfonylpropoxy)-2,6-dimethylphenyl]phenyl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid TAK875 USP/EP/BP [(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]-3-bi... 1000413-72-8 C29H32O7S Inhibitors