Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Mitogen-activated protein kinase (MAPK) >Raf inhibitors >TAK-632

TAK-632

TAK-632 Structure
CAS No.
1228591-30-7
Chemical Name:
TAK-632
Synonyms
CS-854;TAK-632;TAK-0632;TAK-632, >=98%;4-Tetraglucose;TAK 632; TAK632;TAK-632 USP/EP/BP;TAK632 (Free base);TAK2 63 (Free base);N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)
CBNumber:
CB52668801
Molecular Formula:
C27H18F4N4O3S
Molecular Weight:
554.52
MOL File:
1228591-30-7.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:11
Request For Quotation

TAK-632 Properties

Density 1.52±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥27.75 mg/mL in DMSO; insoluble in H2O; ≥2.23 mg/mL in EtOH with gentle warming and ultrasonic
form solid
pka 9.59±0.70(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

TAK-632 Chemical Properties,Uses,Production

Uses

TAK-632 is a selective pan-RAF inhibitor. It exhibits antitumor activity by inducing RAF dimerization but inhibiting its kinase activity in BRAF- and NRAS-mutated with acquired resistance to BRAF inhibitor in human and mouse melanoma cell.

TAK-632 Preparation Products And Raw materials

Raw materials

N-(5-(2-aMino-7-cyanobenzo[d]thiazol-6-yloxy)-2-fluorophenyl)-2-(3-(trifluoroMethyl)phenyl)acetaMide 2-Fluoro-5-nitrobenzonitrile m-(Trifluoromethyl)phenylacetic acid 3-Amino-4-fluorophenol Cyclopropanecarbonyl Chloride

Preparation Products

TAK-632 Suppliers

Global( 108)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Aladdin Scientific 58

TAK-632 Spectrum

TAK-632(1228591-30-7)1HNMR

1228591-30-7(TAK-632)Related Search:

Mobocertinib Tak 799 TAK-960 Soticlestat TAK875
TAK-733 Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]- 6-[(7S)-7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthalenecarboxamide Sorafenib 1,9-Pyrazoloanthrone
Trametinib AZ 628 PP2 CHIR-99021
chevron_left

1of3

chevron_right
TAK-632 N-(7-CYANO-6-(4-FLUORO-3-(2-(3-(TRIFLUOROMETHYL)PHENYL)ACETAMIDO)PHENOXY)BENZO[D]THIAZOL-2-YL)CYCLOPROPANECARBOXAMIDE N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide TAK-0632 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide TAK632 TAK 632 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide TAK-632, >=98% TAK2 63 (Free base) TAK632 (Free base) N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl) Benzeneacetamide, N-[5-[[7-cyano-2-[(cyclopropylcarbonyl)amino]-6-benzothiazolyl]oxy]-2-fluorophenyl]-3-(trifluoromethyl)- N-[7-cyano-6-(4-fluoro-3-{2-[3-(trifluoromethyl)phenyl]acetamido}phenoxy)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide TAK-632 USP/EP/BP 4-Tetraglucose TAK 632; TAK632 CS-854 1228591-30-7 1415800-43-8 C27H18F4N4O3S Inhibitors