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Docetaxel Hydrate

Docetaxel Hydrate Structure
CAS No.
700367-34-6
Chemical Name:
Docetaxel Hydrate
Synonyms
Paclitaxel Impurity 104;(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca3,4benzo1,2-boxet-12-yl benzoate hydrate
CBNumber:
CB52545032
Molecular Formula:
C43H53NO14
Molecular Weight:
807.87922
MOL File:
700367-34-6.mol
Modify Date:
2023/6/8 9:03:09
Request For Quotation

Docetaxel Hydrate Properties

Melting point 170-174°C
storage temp. -20°C Freezer
solubility DMF: 5 mg/ml,DMSO: 5 mg/ml,DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml,Ethanol: 1.5 mg/ml
form A crystalline solid

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P280-P308+P313-P405-P501

Docetaxel Hydrate Chemical Properties,Uses,Production

Description

Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM). It has proven more effective than taxol in preventing the proliferation of cancer cells. Docetaxel has applications in breast cancer and hormone-refractory prostate cancer. This product is intended for research applications.

Chemical Properties

White Solid

Uses

A semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antineoplastic.

Docetaxel Hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Docetaxel Hydrate Suppliers

Global( 9)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8739 58 Inquiry
Toronto Research Chemicals +1 (416) 665-9696 Canada 6088 71 Inquiry
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 96815 76 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56070 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Cayman Chemical Company 81
Shanghai Yifei Biotechnology Co. , Ltd. 58
Toronto Research Chemicals 71
J & K SCIENTIFIC LTD. 76
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58

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Paclitaxel Impurity 104 (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca3,4benzo1,2-boxet-12-yl benzoate hydrate 700367-34-6 C43H53NO14xH2O Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents