ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >Akt inhibitors >GDC-0068

GDC-0068

CAS No.: 1001264-89-6

Chemical Name:: GDC-0068

Synonyms: Ipatasertib;Cenicriviroc mesylate;RG7440;CS-543;GDC-0068;EOS-62198;patasertib;GDC-0068(RG7440);GDC-0068 USP/EP/BP;Ipatasertib (GDC-0068)

CBNumber:: CB52627897

Molecular Formula:: C24H32ClN5O2

Molecular Weight:: 458

MOL File:: 1001264-89-6.mol

Modify Date:: 2023/6/8 9:02:27

Request For Quotation

GDC-0068 Properties

Melting point	>106°C (dec.)
Boiling point	669.4±55.0 °C(Predicted)
Density	1.254
storage temp.	Hygroscopic, Refrigerator, under inert atmosphere
solubility	Soluble in DMSO.
pka	13.11±0.40(Predicted)
form	Solid
color	peachy

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

NFPA 704

	0
2		0

GDC-0068 Chemical Properties,Uses,Production

Uses

GDC-0068 is a highly selective AKT inhibitor targeting Akt1 , Akt2 and Akt3. Studies have shown its use in combination with vemurafenib (V118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.

GDC-0068 Preparation Products And Raw materials

Raw materials

Preparation Products

GDC-0068 Suppliers

Global( 161)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29892	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	China	7132	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24330	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
Pharma Affiliates	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Shanghai UCHEM Inc.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58

GDC-0068 Spectrum

GDC-0068(1001264-89-6)¹HNMR

1001264-89-6(GDC-0068)Related Search:

Cenicriviroc 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol MK-2206 2HCl Alpelisib (BYL719) Pictilisib

AZD5363 Rapamycin

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(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone Ipatasertib (GDC-0068) (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone Ipatasertib (GDC-0068) GDC-0068 (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone (2S)-2-(4-Chlorophenyl)-1-{4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1-piperazinyl}-3-(isopropylamino)-1-propanone Ipatasertib (GDC-0068,RG 7440) GDC-0068;RG7440; GDC0068; GDC 0068; RG-7440; RG 7440 GDC-0068 (Ipatasertib) (S)-2-(4-Chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin- GDC-0068 GDC-0068(RG7440) RG7440 1-Propanone, 2-(4-chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-, (2S)- GDC-0068 USP/EP/BP patasertib GDC0068;GDC 0068;GDC-0068;RG7440;RG-7440;;RG 7440 EOS-62198 GDC-0068, 98%, a highly selective pan-Akt inhibitor CS-543 GDC0068;GDC 0068;GDC-0068 GDC-0068 (Ipatasertib,RG-7440) Ipatasertib Cenicriviroc mesylate GDC-0068 Ipatasertib RG-7440 GDC0068 RG7440 1001264-89-6 1002364-89-6 C24H32ClN5O2 Akt mTOR PI3K Inhibitors Inhibitor PI3K/Akt/mTOR