(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)

CAS No.: 330785-81-4

Chemical Name:: (5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)

Synonyms: Avanafil Intermediate II;ethyl 4-(3-chloro-4-MethoxybenzylaMino)-2-(Methylthio)pyriMidine-5-carboxylate;4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester;AvafilImpurity43;RSYY（Lifitegrast)-1;INTERMEDIATE OF AVANAFIL;Avanafil Intermediate Impurity;330785-81-4;5-Pyrimidinecarboxylicacid, 4-[[(3-chloro-4-methoxyphenyl)me...;4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylthiopyriMidine

CBNumber:: CB52638736

Molecular Formula:: C16H18ClN3O3S

Molecular Weight:: 367.85

MOL File:: 330785-81-4.mol

MSDS File:: SDS

Modify Date:: 2023/9/7 16:59:03

Request For Quotation

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Properties

Boiling point	514.9±45.0 °C(Predicted)
Density	1.33±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka	2.70±0.10(Predicted)
form	powder
color	White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02
Signal word	Warning
Hazard statements	H226
Precautionary statements	P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235
HS Code	2933399990

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Chemical Properties,Uses,Production

Uses

4-(3-Chloro-4-methoxybenzylamino)-5-ethoxycarbonyl-2-methylthiopyrimidine is an intermediate for Avanafil (A794670) derivatives. Avanafil is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Preparation Products And Raw materials

Raw materials

Preparation Products

5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Suppliers

Global( 170)Suppliers

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Supplier	Advantage
CLEANCHEM LABORATORIES LLP	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Shanghai Joiny Pharmaceutical Co.,LTD	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58

330785-81-4((5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester))Related Search:

3-Chloroperoxybenzoic acid INTERMEDIATES Dry shellfish Acetylene Iodixanol

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) 4-(3-Chloro-4-Methoxy-benzylaMino)-2-Methylsulfanyl-pyriMidine-5-carboxylic acid ethyl ester 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylthiopyriMidine Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulphanyl)pyrimidine-5-carboxylate, 4-[(3-Chloro-4-methoxybenzyl)amino]-5-(ethoxycarbonyl)-2-(methylthio)pyrimidine (5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)###NA ethyl 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylate INTERMEDIATE OF AVANAFIL Avanafil intermediates，5-Pyrimidinecarboxylicacid, 4-[[(3- chloro-4- methoxyphenyl)methyl]amino]-2- (methylthio)-, ethyl ester 5-Pyrimidinecarboxylicacid, 4-[[(3-chloro-4-methoxyphenyl)me... "5-Pyrimidinecarboxylic acid,4-[[(3-chloro-4-methoxyphenyl) methyl]amino]-2-(methylthio)ethyl este" 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester ethyl 4-(3-chloro-4-MethoxybenzylaMino)-2-(Methylthio)pyriMidine-5-carboxylate Avanafil Intermediate II AvafilImpurity43 Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate Avanafil Intermediate Impurity RSYY（Lifitegrast)-1 Ethyl 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylate 330785-81-4 4- (3-Chloro-4-methoxyphenylamino) -5-ethoxycarbonyl-2-methylthiapyrimidine 330785-81-4 330785-84-4 330785-81-4