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GSK 2801

GSK 2801 Structure
CAS No.
1619994-68-1
Chemical Name:
GSK 2801
Synonyms
GSK 280;CS-1607;GSK2801;GSK-2801;GSK 2801;GSK2801, >98%;GSK-2801; GSK 280;GSK2801 GSK-2801;GSK2801;GSK-2801;GSK 2801;1-[1-[2-(Methylsulfonyl)phenyl]-7-propoxy-3-indolizinyl]ethanone
CBNumber:
CB52668513
Molecular Formula:
C20H21NO4S
Molecular Weight:
371.45
MOL File:
1619994-68-1.mol
Modify Date:
2024/7/2 8:55:11
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GSK 2801 Properties

Density 1.23±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥2.82 mg/mL in EtOH with gentle warming and ultrasonic
form solid
color Light yellow to khaki

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22

GSK 2801 Chemical Properties,Uses,Production

Description

BAZ2A/B are bromodomain-containing proteins whose biological function is believed to function similarly to ACF1, the Drosophila BAZ2B ortholog. ACF complexes play roles in establishing regular nucleosome spacing during chromatin assembly and influencing different remodeling outcomes at target loci. BAZ2A and BAZ2B constitute the central scaffolding protein of the nucleolar remodeling complex (NoRC) that regulates the expression of noncoding RNAs. GSK2801 is a selective, cell-permeable inhibitor of the BAZ2 family of bromodomain-containing proteins (IC50s = 9-350 nM in a BAZ2B AlphaScreen). It binds to BAZ2A and BAZ2B with Kd values of 0.26 and 0.14 μM, respectively, and does not interact with the bromodomains of BRD4(BD1), CREBBP, TRIM24/TIF1α, PB1(BD5), PCAF, or ATAD2. See the Structural Genomics Consortium (SGC) website for more information.

Uses

GSK2801 is a selective cell-permeable inhibitor of the BAZ2 (bromodomain-containing protein) interfering with nucleosome spacing during chromatin assembly.

GSK 2801 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK 2801 Suppliers

Global( 83)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd +86-18341751992 +86-15382112998 China 892 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 4692 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
TargetMol Chemicals Inc. 58
InvivoChem 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Aladdin Scientific 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58

GSK 2801 Spectrum

GSK 2801(1619994-68-1)1HNMR

1619994-68-1(GSK 2801)Related Search:

GSK2814338 GSK-2256098 GSK-25 S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine
GSK2636771 GSK2879552 GSK2795039 GSK 2330672 GSK2838232
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GSK 2801 GSK2801 GSK-2801 1-(7-(2-Methylsulfonyl-phenyl)-4-propoxy-1-aza-bicyclo[4.3.0]nona-2,4,6,8-tetraen-9-yl)-ethanone 1-(1-(2-(methylsulfonyl)phenyl)-7-propoxyindolizin-3-yl)ethanone 1-[1-[2-(Methylsulfonyl)phenyl]-7-propoxy-3-indolizinyl]ethanone Ethanone, 1-[1-[2-(methylsulfonyl)phenyl]-7-propoxy-3-indolizinyl]- GSK-2801; GSK 280 GSK 280 GSK2801, >98% CS-1607 GSK2801;GSK-2801;GSK 2801 1-[1-(2-Methanesulfonyl-phenyl)-7-propoxy-indolizin-3-yl]-ethanone GSK2801 GSK-2801 inhibit,Inhibitor,GSK-2801,TNBC,BAZ2A,GSK2801,Epigenetic Reader Domain,Apoptosis,BAZ2B,cetyl-lysine,orally,GSK 2801 1619994-68-1 Inhibitors