cefsulodin sodium salt
- CAS No.
- 52152-93-9
- Chemical Name:
- cefsulodin sodium salt
- Synonyms
- Ulfar;sce129;ulfaret;pyocefal;cgp7174e;monaspor;tilmapor;pseudocef;takesulin;cefomonil
- CBNumber:
- CB5270251
- Molecular Formula:
- C22H19N4O8S2.Na
- Molecular Weight:
- 554.53
- MOL File:
- 52152-93-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:04
Melting point | 175 C |
---|---|
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | H2O: 50 mg/mL, clear, light yellow |
form | powder or crystals |
color | Off-White to Pale Yellow |
Water Solubility | Soluble in water. |
Merck | 13,1958 |
Stability | Hygroscopic |
InChIKey | REACMANCWHKJSM-DWBVFMGKSA-M |
EPA Substance Registry System | Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-phenylsulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, monosodium salt (52152-93-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08,GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H317-H319-H335-H334 |
Precautionary statements | P261-P280-P305+P351+P338-P280g-P284-P304+P340-P342+P311a-P501a |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-42/43-20/21/22 |
Safety Statements | 22-26-36/37-45-36 |
WGK Germany | 2 |
RTECS | UU1785000 |
TSCA | Yes |
HS Code | 29419059 |
Toxicity | LD50 in mice (mg/kg): >4000 i.p.; >15000 orally (Bryskier) |
cefsulodin sodium salt price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C8145 | Cefsulodin sodium salt hydrate third-generation cephalosporin antibiotic | 52152-93-9 | 100MG | ₹6018.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C8145 | Cefsulodin sodium salt hydrate third-generation cephalosporin antibiotic | 52152-93-9 | 250MG | ₹8660 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C8145 | Cefsulodin sodium salt hydrate third-generation cephalosporin antibiotic | 52152-93-9 | 1G | ₹22321.15 | 2022-06-14 | Buy |
SRL | 80223 | Cefsulodin Sodium Salt (CFS) extrapure, 97% | 52152-93-9 | 10mg | ₹3120 | 2022-05-26 | Buy |
SRL | 80223 | Cefsulodin Sodium Salt (CFS) extrapure, 97% | 52152-93-9 | 250mg | ₹7490 | 2022-05-26 | Buy |
cefsulodin sodium salt Chemical Properties,Uses,Production
Description
Cefsulodin was synthesized by Takeda Chemicals Industries in 1974 by introducing the sulfobenzyl group, the same moiety as in sulbenicillin, at the 7 position of the cephem nucleus. Its side chain at the 3 position is similar to that of cephaloridine except for the carbamoyl group. The introduction of these hydrophilic groups increases the activity against Pseudomonas aeruginosa, but it markedly decreases it against gram-positive and other gramnegative bacteria. Therefore cefsulodin is used as a specific antibiotic against infections caused by the opportunistic pathogen P. aeruginosa.
Uses
Cefsulodin is most commonly used in CIN agar to select for Yersinia microorganisms. The compound displays a mechanism of action like many β lactam antibiotics through inhibition of cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) crosslinking of peptidoglycan resulting in inhibition of the final transpeptidation step. Through the inability for Cefsulodin sodium salt hydrate to inhibit cefsulodin-resistant mutants of Pseudomonas aeruginosa PAO4089 growth displayed that Cefsulodin sodium salt hydrate may compete with PBP3 in addition to PBP1A and PBP1B.
cefsulodin sodium salt Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
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