Raffinose
- CAS No.
- 512-69-6
- Chemical Name:
- Raffinose
- Synonyms
- D-RAFFINOSE;melitriose;Cottonseed oligosaccharides;ffinose;NSC 2025;NSC26414;RAFFINOSE;gossypose;NSC-26414;NSC 26414
- CBNumber:
- CB5290712
- Molecular Formula:
- C18H32O16
- Molecular Weight:
- 504.44
- MOL File:
- 512-69-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/21 13:10:12
| Melting point | 81℃ |
|---|---|
| Boiling point | 513.84°C (rough estimate) |
| Density | 1.81 |
| refractive index | 1.6760 (estimate) |
| storage temp. | 2-8°C |
| solubility | |DMSO : 100 mg/mL (198.24 mM; Need ultrasonic) |
| form | Solid |
| pka | pK1:12.74 (25°C) |
| color | White to Off-White |
| Water Solubility | 229.8g/L(25 ºC) |
| Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
| LogP | -5.104 (est) |
| CAS DataBase Reference | 512-69-6(CAS DataBase Reference) |
| EPA Substance Registry System | .alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl O-.alpha.-D-galactopyranosyl-(1.fwdarw.6)- (512-69-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P501-P270-P264-P301+P312+P330 |
| Safety Statements | 24/25 |
| HS Code | 29389090 |
Raffinose Chemical Properties,Uses,Production
Chemical Properties
Raffinose is a white crystalline powder. It is odorless and has a sweet taste approximately 10% that of sucrose.
Uses
D-(+)-Raffinose is an oligosaccharide and trisaccharide whose physical structure and chemical properties have been shown to affect the stability and crystallization of amorphous sucrose, helping to increase the shelf-life of sucrose-containing foods.
Production Methods
Raffinose occurs naturally in Australian manna, cottonseed meal, and seeds of various food legumes. It can be isolated from beet sugar molasses through sucrose separation, seed-crystallization, and filtration.
Pharmaceutical Applications
Raffinose is a trisaccharide carbohydrate that is used as a bulking agent, blood substitute, stabilizing agent, and water scavenger in freeze-drying where it acts as a stabilizer for freeze-dried formulations. It is also used as a crystallization inhibitor in sucrose solutions.
Safety
Raffinose is a naturally occurring trisaccharide investigated for use in freeze-dried pharmaceutical formulations. It occurs in a number of plants that are consumed widely.
storage
Raffinose is stable under ordinary conditions of use and storage. Excessive heat should be avoided to prevent degradation. Thermal decomposition products are carbon monoxide and carbon dioxide.
Purification Methods
fructo-furanose [17629-30-0 (5H2O), 512-69-6 (anhydrous)] M 594.5, m 8 0o, 80 -82o, +124o (c 10, H2O), [ ] D +105o (c 1 for pentahydrate, H2O), pK 1 12.40, pK 2 13.44, pK 3 13.52. D(+)-Raffinose crystallises from H2O, 90% aqueous EtOH or MeOH as the pentahydrate. The anhydrous sugar has m 132-135o. It has RF 0.8 on TLC (Silica Gel, and 1:3:3 CHCl3/butanone:/MeOH). The undecaacetate has been purified through an alumina column by elution with CHCl3, and recrystallised from EtOH/MeOH/H2O (3:2:5), with m 99-100o, [] D +92.8o (c 5.14, EtOH). [pK : Coccioli & Vicedomini Ann Chim (Rome) 66 269, 275 1976, 1H NMR: Suami et al. Carbohydr Research 26 234 1973, Beilstein 17 III/IV 3801, 17/8 V 403.]
Incompatibilities
Raffinose is incompatible with strong oxidizers.
Regulatory Status
Raffinose is a naturally occurring trisaccharide and is consumed as part of a normal diet.
Raffinose Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12453 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2989 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8822 | 58 | Inquiry |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
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