DIHYDROCYCLOSPORIN A
- CAS No.
- 59865-15-5
- Chemical Name:
- DIHYDROCYCLOSPORIN A
- Synonyms
- CS-2523;Cyclosporin EP B;Dihydrocyclosporin;Capecitabine Imp.G;DIHYDROCYCLOSPORIN A;Dihydrocyclosporine A;Cyclosporin Impurity 10;Cyclosporine Impurity 10;Ciclosporin EP impurity B;Dihydrocyclosporin A reference
- CBNumber:
- CB5352728
- Molecular Formula:
- C62H113N11O12
- Molecular Weight:
- 1204.63
- MOL File:
- 59865-15-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/6 15:55:14
| Melting point | 120-125?C |
|---|---|
| Boiling point | 1285.3±65.0 °C(Predicted) |
| Density | 1.012±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.33±0.70(Predicted) |
| color | White |
| InChIKey | TYFOVYYNQGNDKH-AAJDKDKZNA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H350-H302-H362 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313 |
DIHYDROCYCLOSPORIN A Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections.
Uses
Dihydrocyclosporin A (DHCsA-d) is cyclosporine A (CsA) derivative. DHCsA-d significantly inhibited promastigotes and intracellular amastigotes, but it is highly cytotoxic.
Side effects
Dihydrocyclosporine A has no obvious nephrotoxic effect, but it exhibits hepatotoxic effects, often leading to hypertension.
DIHYDROCYCLOSPORIN A Preparation Products And Raw materials
Global( 89)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
| SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Hebei Duling International Trade Co. LTD | +8617333973358 | China | 15438 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
59865-15-5(DIHYDROCYCLOSPORIN A)Related Search:
DIHYDROCYCLOSPORIN A
Dihydrocyclosporin
(3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-]
(3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)
6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A
Cyclosporin A Dihydro IMpurity
Dihydrocyclosporine A
Cyclosporin Impurity 10
Dihydrocyclosporin A reference
Dihydrocyclosporine A/6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A
CS-2523
Cyclosporin Impurity 10（Dihydrocyclosporin A）
Cyclosporin A,6-[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoic acid]-
Capecitabine Imp.G
Cyclosporine Impurity 10
Ciclosporin EP impurity B
Cyclosporin Impurity 10(Dihydrocyclosporin A)(Ciclosporin EP Impurity B)
Ciclosporin EP Impurity B (Dihydrocyclosporin A)
Cyclosporin EP B
59865-15-5
C62H113N11O12
Intermediates & Fine Chemicals
Peptides
Pharmaceuticals