ANISOMYCIN
- CAS No.
- 22862-76-6
- Chemical Name:
- ANISOMYCIN
- Synonyms
- Nsc76712;Nsc147340;Aids031977;ANISOMYCIN;FLAGECIDIN;Aids-031977;Wuningmeisu C;4-beta))-alph;Anisomycin>(-)-anisomycin
- CBNumber:
- CB5363672
- Molecular Formula:
- C14H19NO4
- Molecular Weight:
- 265.3
- MOL File:
- 22862-76-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/29 17:48:59
| Melting point | 140-141 C |
|---|---|
| Boiling point | 408.52°C (rough estimate) |
| alpha | D23 -30° (methanol) |
| Density | 1.1356 (rough estimate) |
| refractive index | 1.5230 (estimate) |
| Flash point | 87℃ |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | methanol: 20 mg/mL, clear, colorless to faintly yellow |
| form | solid |
| pka | 7.9(at 25℃) |
| color | white |
| Water Solubility | Soluble in water at 2 mg/ml, in DMSO at 20mg/ml, and in methanol at 20mg/ml |
| λmax | 283nm(EtOH)(lit.) |
| Merck | 14,670 |
| BRN | 20705 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | YKJYKKNCCRKFSL-RDBSUJKOSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T,Xn | |||||||||
| Risk Statements | 25-36/37/38-20/21/22 | |||||||||
| Safety Statements | 45-36-26 | |||||||||
| RIDADR | UN 3462 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | BZ9800000 | |||||||||
| F | 3-10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29419090 | |||||||||
| Toxicity | LD50 orl-rat: 72 mg/kg ANTCAO 5,490,55 | |||||||||
| NFPA 704 |
|
ANISOMYCIN price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A9789 | Anisomycin from Streptomyces griseolus ≥98% (HPLC), solid | 22862-76-6 | 5MG | ₹5877.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9789 | Anisomycin from Streptomyces griseolus ≥98% (HPLC), solid | 22862-76-6 | 25MG | ₹19095.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9789 | Anisomycin from Streptomyces griseolus ≥98% (HPLC), solid | 22862-76-6 | 100MG | ₹57762.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A5862 | Anisomycin, Ready Made Solution from Streptomyces griseolus 10?mg/mL in DMSO | 22862-76-6 | 0.5ML | ₹7208.6 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A2613 | Anisomycin min. 96.0 % | 22862-76-6 | 25MG | ₹10100 | 2022-05-26 | Buy |
ANISOMYCIN Chemical Properties,Uses,Production
Chemical Properties
Crystalline
Uses
Anisomycin is a phenylmethylenepyrrolidine first isolated from Streptomyces griseolus in 1954 as an antiprotozoan with antifungal activity. Anisomycin is an inhibitor of protein synthesis by binding to the 60S ribosomal subunit. Interestingly, anisomycin has found use for the induction of amnesia in animal models. More recently, anisomycin has been demonstrated to induce apoptosis, to be a selective signalling agonist, to activate mitogen-activated protein (MAP) kinases and to be immunomodulatory via its action on T cells.
Definition
ChEBI: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
Biological Activity
Protein synthesis inhibitor (blocks translation). Potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. Acts as a potent signaling agonist to selectively elicit homologous desensitization of immediate early gene induction (c-fos, fosB, c-jun, junB and junD).
Safety Profile
Poison by ingestion,intraperitoneal, subcutaneous, and intravenous routes.When heated to decomposition it emits toxic fumes ofNOx.
ANISOMYCIN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 280)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1843 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Biopharmacule Speciality Chemicals P Ltd (India) | +91 40 6462 1866 | Hyderabad, India | 526 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Apeloa production Co.,Limited | +8619933239880 | China | 853 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
22862-76-6(ANISOMYCIN)Related Search:
Ciprofloxacin hydrochloride
ANISOMYCIN
(R)-3-METHOXYPYRROLIDINE
(3S,4S)-Pyrrolidine-3,4-diol
3-PHENYLPROPYL ACETATE
4-(4-METHOXYPHENYL)-1-BUTANOL
4-PHENYL-2-BUTYL ACETATE
3-METHOXYPYRROLIDINE
3-PHENYLPROPYL FORMATE
3-ETHOXYPYRROLIDINE
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(2R,3S,4S)-2-(4-METHOXYBENZYL)-3,4-PYRROLIDINEDOIL-3-ACETATE
(2R,3S,4S)-2-[(4-METHOXYPHENYL)METHYL]-3,4-PYRROLIDINEDIOL 3-ACETATE
2-(P-METHOXYBENZYL)-3,4-PYRROLIDINEDIOL-3-ACETATE
2-P-METHOXYPHENYLMETHYL-3-ACETOXY-4-HYDROXYPYRROLIDINE
1,4,5-trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate
ANISOMYCIN FROM STREPTOMYCES GRISEOLUS
3,4-Pyrrolidinediol, 2-(4-methoxyphenyl)methyl-, 3-acetate, (2R,3S,4S)-
(2R,3S,4S)-2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate
(2R)-2α-(4-Methoxybenzyl)pyrrolidine-3α,4β-diol 3-acetate
1,4-Imino-5-(4-methoxyphenyl)1,4,5-trideoxy-D-xylo-pentitol 3-acetate
Acetic acid (2R)-4β-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3α-yl ester
2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol-3-acetate
D-xylo-Pentitol, 1,4,5-trideoxy-1,4-imino-5-(4-methoxyphenyl)-, 3-acetate
Aids031977
Aids-031977
Nsc147340
Nsc76712
(2R,3S,4S)-4-hydroxy-2-(4-Methoxybenzyl)pyrrolidin-3-yl acetate
Flagecidin, SA 3097C1, PA 106, Anhydroscopin A, NSC 76712
(2R,3S,4S)-2-(p-Methoxyphenylmethyl)-3-acetoxy-4-hydroxypyrrolidine
Wuningmeisu C
(2S,3R,4R)-2-(4-methoxybenzyl)-4-hydroxypyrrolidin-3-yl acetate
NSC 76712 Anisomycin Flagecidin
2-((4-methoxyphenyl)methyl)-,3-acetate,(2r-(2-alpha,3-4-pyrrolidinediol
2-(p-methoxybenzyl)-,3-acetate,(2s,3r,4r)-4-pyrrolidinediol
4-beta))-alph
antibioticpa-106
ANISOMYCIN, STREPTOMYCES GRISEOLUS
ANISOMYCIN
FLAGECIDIN
(2R,3S,4S)-2-(4-METHOXYBENZYL)-3,4-PYRROLIDINEDIOL-3-ACETATE
Anisomycin, Ready Made Solution from Streptomyces griseolus
Anisomycin (from Streptomyces griseolus)≥ 98% (HPLC)
Anisomycin, Streptomyces griseolus - CAS 22862-76-6 - Calbiochem
FLAGECIDIN;WUNINGMEISU C
Anisomycin
(Flagecidin
Anisomycin, 99%, from Streptomyces griseolus
Anisomycin Anisomycin
Anisomycin>
ANISOMYCIN USP/EP/BP
Anisomycin (NSC-76712, AI 3-50846, Flagecidin, Wuningmeisu C)
Anisomycin, ≥98% (HPLC)
(-)-anisomycin
22862-76-6
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