ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Proline derivatives >Boc-Hyp-OH
Boc-Hyp-OH
![Boc-Hyp-OH Structure](CAS/GIF/13726-69-7.gif)
- CAS No.
- 13726-69-7
- Chemical Name:
- Boc-Hyp-OH
- Synonyms
- (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid;BOC-HYP-OH;BOC-HYP;BOC-L-HYP-OH;N-BOC-L-HYDROXYPROLINE;(4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline;(2S,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylic Acid;N-ter;Teneint-E;oc-L-Hyp-OH
- CBNumber:
- CB5411793
- Molecular Formula:
- C10H17NO5
- Molecular Weight:
- 231.25
- MOL File:
- 13726-69-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/26 21:18:56
Melting point | 123-127 °C(lit.) |
---|---|
Boiling point | 390.9±42.0 °C(Predicted) |
alpha | -78 º (in H2O) |
Density | 1.312±0.06 g/cm3(Predicted) |
refractive index | -68 ° (C=1, MeOH) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
pka | 3.80±0.40(Predicted) |
form | Powder |
color | White to off-white |
optical activity | [α]20/D 53.5±2°, c = 1% in DMF |
Water Solubility | very faint turbidity |
BRN | 4295484 |
InChIKey | BENKAPCDIOILGV-RQJHMYQMSA-N |
CAS DataBase Reference | 13726-69-7(CAS DataBase Reference) |
EPA Substance Registry System | (2S,4R)-1-tert-Butyl 4-hydroxy-1,2-pyrrolidinecarboxylate (13726-69-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Safety Statements | 22-24/25 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 2933 99 80 | |||||||||
HazardClass | IRRITANT | |||||||||
NFPA 704 |
|
Boc-Hyp-OH price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 8.53026 | Boc-Hyp-OH (cryst) Novabiochem? | 13726-69-7 | 25G | ₹25940 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.53026 | Boc-Hyp-OH (cryst) Novabiochem? | 13726-69-7 | 100G | ₹77250 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 15544 | Boc-Hyp-OH ≥98.0% (TLC) | 13726-69-7 | 5G | ₹5477.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 15544 | Boc-Hyp-OH ≥98.0% (TLC) | 13726-69-7 | 25G | ₹18846.33 | 2022-06-14 | Buy |
TCI Chemicals (India) | B1635 | trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline | 13726-69-7 | 5G | ₹5800 | 2022-05-26 | Buy |
Boc-Hyp-OH Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Boc-Hyp-OH is used in the preparation of hydroxyproline derivatives. It is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
Biological Activity
Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Boc-Hyp-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 492)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
SURVIVAL TECHNOLOGIES LIMITED | +91 8108285261 | Gujarat, India | 294 | 58 | Inquiry |
BTC pharm India | +918790379245 | Telangana, India | 145 | 58 | Inquiry |
VGS SYNTHESIS PRIVATE LIMITED | +91-9866975588 +91-9866975588 | Hyderabad, India | 1818 | 58 | Inquiry |
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
Malladi Drugs AND Pharmaceuticals Limited | +91-9004653310 +91-9003056437 | Tamil Nadu, India | 69 | 58 | Inquiry |
ARRKEM LIFE SCIENCES PRIVATE LIMITED | +91-8148739767 +91-8148739767 | Telangana, India | 260 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
13726-69-7(Boc-Hyp-OH)Related Search:
L-Hydroxyproline
BOC-D-PHE-OSU
Boc-D-Valine
1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER
Methyl N-(tert-butoxycarbonyl)-L-threoninate
Boc-L-serine methyl ester
BOC-GUANIDINE
BOC-L-HYDROXYPROLINE METHYL ESTER,(2S,4R)-BOC 4-HYDROXYPROLINE METHYL ESTER,BOC-HYP-OME / BOC-L-HYDROXYPROLINE METHYL ESTER
BOC-HYP(BZL)-OH
1-Boc-L-hydroxyproline ethyl ester
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(2S,4R)-N-t-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid
Boc-(2S,4R)-4-Hydroxy-2-pyrrolidinecarboxylic Acid
N-ter
N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline ,98%
Boc-L-trans-hydroxyproline(Boc-trans-Hyp-OH) ,98.5%(HPLC)
1,2-Pyrrolidinedicarboxylicacid,4-hydroxy-,1-(1,1-diMethylethyl)ester,(2S,4R)-
(2S)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
trans-N-Boc-4-hydroxy-L-proline
trans-Boc-Hyp-OH
(2S,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) ester
(2S,4R)-1-(tertbutoxycarbonyl-4-hydroxypyrrolidine acid
Boc-Hyp-OH, >=98.0%
trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline
N-Boc-(2S,4R)-4-hydroxyproline
BOC-(2S,4R)-(-)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
BOC-L-HYDROXYPROLINE
BOC-L-4-HYDROXYPROLINE
BOC-HYDROXYPROLINE
BOC-TRANS-HYP-OH
BOC-TRANS-4-HYDROXY-L-PROLINE
BOC-L-T-4-HYDROXYPROLINE
BOC-L-TRANS-4-HYDROXYPROLINE
Boc-L-trans-4-hydroxyproline≥ 99% (Assay)
Boc-Hyp-OH (cryst) Novabiochem
Boc-Hyp-OH >=98.0% (TLC)
(2S,4R)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
RARECHEM EM WB 0136
N-T-BOC-TRANS-4-HYDROXY-L-PROLINE
N-(TERT-BUTOXYCARBONYL)-L-4-HYDROXYPROLINE
N-TERT-BUTOXYCARBONYL-L-HYDROXYPROLINE
N-ALPHA-TERT-BUTYLOXYCARBONYL-L-4-HYDROXYPROLINE
N-ALPHA-T-BUTOXYCARBONYL-TRANS-4-HYDROXY-L-PROLINE
(2S,4R)-1-(tertbutoxycarbonyl)-4-hydroxypyrrolidine carboxylic acid
BOC-HYPOZANTHINE extrapure
Boc-L-hydroxyproline, trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline
trans-Boc-Hyp-OH
trans-N-Boc-4-hydroxy-L-proline
1-[(tert-Butoxy)carbonyl]-4-hydroxy-L-proline
N-ALPHA-T-BOC-TRANS-4-HYDROXY-L-PROLINE
N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE
N-ALPHA-T-BOC-L-HYDROXYPROLINE
N-ALPHA-T-BOC-L-TRANS-4-HYDROXYPROLINE
N-BOC-TRANS-4-HYDROXY-L-PROLINE
N-BOC-L-4-HYDROXYPROLINE
N-BOC-L-TRANS-4-HYDROXYPROLINE
N-BOC-4-HYDROXY-L-PROLINE
TRANS-N-(TERT-BUTOXYCARBONYL)-4-HYDROXY-L-PROLINE
Butoxycarbonylhydroxypyroline
Boc-4-hydroxy-L-proline
TRANS-N-(TERT-BUTOXYCARBONYL)-4-HYDROXY-
N-(TERT-BUTOXYCARBONYL)-L-4-HYDROXYPROLINEBOC-L-HYP-OH
TERT-BUTYLOXYCARBONYLHYDROXYPROLINE
4-hydroxy-1-tert-butoxycarbonyl-pyrrolidine-2-carboxylic acid
N-ALPHA-T-BUTYLOXYCARBONYL-L-4-HYDROXYPROLINE
BOC TRANS 4 HYDROXY L PROLINE, METHYL ESTER (BOC H
NALPHA-tert-Butoxycarbonyl-trans-4-hydroxy-L-proline
N-tert-Butoxycarbonyl-Trans-4-hydroxy-L-proline
(Tert-Butoxy)Carbonyl Hyp-OH (Hyp of Animal Origin)
(Tert-Butoxy)Carbonyl Hyp-OH (Hyp of Non-Animal Origin)