4-isopropylcyclohexanol
- CAS No.
- 4621-04-9
- Chemical Name:
- 4-isopropylcyclohexanol
- Synonyms
- APO PATCHONE;APOPATCHONE, IFF;Folrosia 5094001;TIMTEC-BB SBB008023;4-ISPROPYLCYCLOHEXANOL;Isopropyl cyclohexanol;p-isopropyl-cyclohexano;P-ISOPROPYL CYCLOHEXANOL;4-ISO-PROPYLCYCLOHEXANOL;Isopropylcyclohexanol, p-
- CBNumber:
- CB5428740
- Molecular Formula:
- C9H18O
- Molecular Weight:
- 142.24
- MOL File:
- 4621-04-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/28 11:23:46
| Melting point | 36.9°C (estimate) |
|---|---|
| Boiling point | 110°C/22mmHg(lit.) |
| Density | 0.9103 (estimate) |
| vapor pressure | 4.73-6.3Pa at 20-25℃ |
| refractive index | gt. 1.4660 to 1.4700 |
| Flash point | 95 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Almost insoluble in water, soluble in alcohol and oils |
| form | clear liquid |
| pka | 15.30±0.40(Predicted) |
| color | Colorless to Almost colorless |
| Odor | at 10.00 % in dipropylene glycol. leather red rose green dusty weedy metallic |
| Odor Type | leathery |
| LogP | 2.7-2.8 at 35℃ |
| Surface tension | 36.7mN/m at 1g/L and 20℃ |
| EPA Substance Registry System | Cyclohexanol, 4-(1-methylethyl)- (4621-04-9) |
4-isopropylcyclohexanol Chemical Properties,Uses,Production
Uses
4-isopropylcyclohexanol has been suggested for use in perfume compositions on account of its power, low cost, and stability in soap. It has acceptable effects upon Lavender, Pine and even on Rose type fragrances for such purpose, but it needs proper blending with sweetening materials of similar volatility, e.g. Linalool, Phenylethyl alcohol, Anethole, Citronellol, esters, etc. It blends well with the conventional Fougère materials and with many of the newer Cyclohexane derivatives.
Preparation
1) by hydrogenation of para-iso-Propyl phenol.
2) by electrolytic reduction of Cryptone,
which can be obtained as an isolate from
Eucalyptus oil fractions or certain Pine
needle oils.
Biochem/physiol Actions
4-isopropylcyclohexanol (4-iPr-CyH-OH), a novel analgesic compound , which inhibited TRPV1, TRPA1, TRPM8, TRPV4 and ANO1, as well as mitigated capsaicin-induced pain-related behaviors in mice. Moreover, the absence of an agonist effect for 4-iPr-CyH-OH on these five channels may reduce side effects and dosages[1].
References
[1] Yasunori Takayama, M. Tominaga, H. Furue. “4-isopropylcyclohexanol has potential analgesic effects through the inhibition of anoctamin 1, TRPV1 and TRPA1 channel activities.” Scientific Reports (2017).
4-isopropylcyclohexanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12459 | 58 | Inquiry |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +86-86177 | China | 2952 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | China | 2141 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8826 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 4088 | 58 | Inquiry |