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4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Structure
CAS No.
39731-05-0
Chemical Name:
4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
Synonyms
SDZ 21009;Carpindolol;Isopropyl 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylate;4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester;4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylicacid,1-methylethyleste;4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER;1H-Indole-2-carboxylic acid, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, 1-methylethyl ester
CBNumber:
CB5448519
Molecular Formula:
C19H28N2O4
Molecular Weight:
348.44
MOL File:
39731-05-0.mol
Modify Date:
2023/7/12 16:42:15
Request For Quotation

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Properties

Boiling point 529.8±50.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 100 mM in ethanol and to 100 mM in DMSO
form Powder
pka pKa 8.75 (Uncertain)

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Chemical Properties,Uses,Production

Uses

SDZ 21009 is a 5-HT1A/1B antagonist.

Biological Activity

β -adrenoceptor and 5-HT 1A/1B receptor antagonist. pK B /pA 2 values are 8.3 and 8.0 for 5-HT 1A and 5-HT 1B receptors respectively. Centrally active following systemic administration in vivo .

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Suppliers

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39731-05-0(4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER)Related Search:

4-Methoxy-1H-indole-2-carboxylic acid rac Mepindolol-d7 4-Hydroxy-2-methylindole METHYL 4-METHOXY-2-INDOLECARBOXYLATE 4-methoxy-2-methyl-1H-indole
4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Pindolol
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SDZ 21009 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Carpindolol 4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester 4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylicacid,1-methylethyleste 1H-Indole-2-carboxylic acid, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, 1-methylethyl ester Isopropyl 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylate 39731-05-0 C19H28N2O4