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2-CHLORO-N-METHYLACETOACETAMIDE

2-CHLORO-N-METHYLACETOACETAMIDE Structure
CAS No.
4116-10-3
Chemical Name:
2-CHLORO-N-METHYLACETOACETAMIDE
Synonyms
1-Chloroacetoacetomethylamine;A-ChloroAcetoN-Methylacetamide;2-chloro-n-ethyl-acetoacetamid;N-Methyl-2-chloroacetoacetamide;2-CHLORO-N-METHYLACETOACETAMIDE;α-chloro aceto N-methylacetamide;N-Methyl-2-chloro-3-oxobutanamide;2-chloro-N-methyl-3-oxobutyramide;2-chloro-3-keto-N-methyl-butyramide;alpha-chloracetessigsaeureaethylamid
CBNumber:
CB5502549
Molecular Formula:
C5H8ClNO2
Molecular Weight:
149.58
MOL File:
4116-10-3.mol
MSDS File:
SDS
Modify Date:
2023/6/4 8:28:38

2-CHLORO-N-METHYLACETOACETAMIDE Properties

Melting point 78-80 °C
Boiling point 284.1±30.0 °C(Predicted)
Density 1.2253 (rough estimate)
refractive index 1.5500 (estimate)
pka 10.01±0.46(Predicted)
EPA Substance Registry System 2-Chloro-N-methyl-3-oxobutanamide (4116-10-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501
Hazard Codes  T
Risk Statements  22-24-37/38-41-43
Safety Statements  26-28-36/37/39-45
RIDADR  2923
RTECS  AK3910000
HazardClass  8
PackingGroup  III
Toxicity mouse,LD50,oral,750mg/kg (750mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: ANTIPSYCHOTIC,Archiv fuer Toxikologie. Vol. 18, Pg. 316, 1960.

2-CHLORO-N-METHYLACETOACETAMIDE Chemical Properties,Uses,Production

Uses

2-Chloro-N-methyl-3-oxo-butanamide is used in the preparation of piperidinylmethyl (thiazolyl)phenylcarbamates which are useful as M3 muscarinic acetylcholine receptor antagonists for the treatment of chronic obstructive lung diseases, chronic bronchitis, asthma, and other disease.

2-CHLORO-N-METHYLACETOACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 15)Suppliers
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alpha-chloroacetoaceticacidmonoethylamide 2-chloro-N-methyl-3-oxobutyramide N-Methyl-2-chloroacetoacetamide 1-Chloroacetoacetomethylamine A-ChloroAcetoN-Methylacetamide α-chloro aceto N-methylacetamide N-Methyl-2-chloro-3-oxobutanamide 2-chloro-3-keto-N-methyl-butyramide 2-CHLORO-N-METHYLACETOACETAMIDE 2-chloro-n-ethyl-acetoacetamid alpha-chloracetessigsaeureaethylamid Butanamide, 2-chloro-N-methyl-3-oxo- 4116-10-3 C5H8ClO2