ChemicalBook > Product Catalog >Organic Chemistry >Amides >Naphthenic amines derivatives >Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

CAS No.: 67579-81-1

Chemical Name:: Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine

Synonyms: (1R,2R)-N1,N2-dimethylcyclohexane-1,2-diamine;t-DMACH;trans-N1,N2-DiMethylcyclohexane-1,2-diaMine;trans-N,N;TRANS-1,2-BIS(METHYLAMINO)CYCLOHEXANE;TRANS-N,N'-DIMETHYLCYCLOHEXANE-1,2-DIAMINE;trans-N,N'-DimethyL;TRANS-N,N'-DIMETHYLCYCLOHEXANE;(1R,2R)-rel-N1,N2-Dimethyl-1,2-cycloh;trans-N,N'-DiMethylcyclohexane-1,2-diaMin

CBNumber:: CB5674518

Molecular Formula:: C8H18N2

Molecular Weight:: 142.24

MOL File:: 67579-81-1.mol

MSDS File:: SDS

Modify Date:: 2024/4/12 23:00:59

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Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine Properties

Melting point	4°C
Boiling point	83 °C / 13mmHg
Density	0.89
refractive index	n20/D1.472(lit.)
Flash point	60℃
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
pka	11.04±0.40(Predicted)
form	liquid
color	colorless to pale yellow
Sensitive	air sensitive
InChI	InChI=1/C8H18N2/c1-9-7-5-3-4-6-8(7)10-2/h7-10H,3-6H2,1-2H3/t7-,8-/s3
InChIKey	JRHPOFJADXHYBR-HTQZYQBOSA-N
SMILES	[C@@H]1(NC)CCCC[C@H]1NC \|&1:0,7,r\|
CAS DataBase Reference	67579-81-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H314

Precautionary statements

P270-P280-P301+P312-P301+P330+P331-P303+P361+P353-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38-34-22

Safety Statements

26-36/37/39-45

RIDADR

2735

WGK Germany

HazardClass

PackingGroup

Ⅱ

HS Code

2921309990

NFPA 704

	2
3		0

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	633089	trans-N,N′-Dimethylcyclohexane-1,2-diamine 97%	67579-81-1	5ML	₹18153.53	2022-06-14	Buy
Sigma-Aldrich(India)	633089	trans-N,N′-Dimethylcyclohexane-1,2-diamine 97%	67579-81-1	5ML	₹18153.53	2022-06-14	Buy
Sigma-Aldrich	633089	trans-N,N′-Dimethylcyclohexane-1,2-diamine 97%	67579-81-1	25ML	₹69593.93	2022-06-14	Buy
Sigma-Aldrich(India)	633089	trans-N,N′-Dimethylcyclohexane-1,2-diamine 97%	67579-81-1	25ML	₹69593.93	2022-06-14	Buy
Sigma-Aldrich(India)	633089	trans-N,N′-Dimethylcyclohexane-1,2-diamine 97%	67579-81-1	100ML	₹211704.53	2022-06-14	Buy

Product number	Packaging	Price	Buy
633089	5ML	₹18153.53	Buy
633089	5ML	₹18153.53	Buy
633089	25ML	₹69593.93	Buy
633089	25ML	₹69593.93	Buy
633089	100ML	₹211704.53	Buy

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine Chemical Properties,Uses,Production

Description

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine is a useful research chemical for organic synthesis and other chemical processes.

Uses

trans-N,N′-dimethylcyclohexane-1,2-diamine can be used as a ligand in the synthesis of the following products via copper catalyzed C-N coupling reactions:

vinylsulfoximines obtained from NH sulfoximes and vinyl bromides
N-arylpyridones obtained via reaction between 2-substituted pyridines and aryl halides
N-aryl amines obtained via reaction between amines and aryl iodides/aryl bromides

Synthesis

Cyclohexene oxide (1) was reacted with 25–30% aqueous methylamine (1.5 equiv.) in a sealed reactor to form trans-2-(methylamino)cyclohexanol 2 at 80 °C within 5h. Compound 2 was subjected to Mitsunobu reaction at room temperature, followed by adjusting the pH from 2 to 10 to yield 7-methyl-7-azabicyclo[4.1.0]-heptane 3, which was directly subjected to the following reaction without purification. Ring-opening reactions of compound 3 with a methylamine aqueous solution were completed in a sealed reactor at 110 °C after 6h to yield Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine.

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine Suppliers

Global( 230)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Reax Chemicals	08048372701Ext 416	Hyderabad, India	4223	58	Inquiry
Clearsynth Labs	91-22-45045900	Maharashtra, India	3889	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Wuhan Konberd Biotech Co., Ltd	+undefined18986093962	China	1376	58	Inquiry
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	China	6990	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	16209	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21669	55	Inquiry

Supplier	Advantage
TCI Chemicals (India) Pvt. Ltd.	58
Reax Chemicals	58
Clearsynth Labs	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Wuhan Konberd Biotech Co., Ltd	58
Shanghai UCHEM Inc.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine Spectrum

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine(67579-81-1)¹HNMR

67579-81-1(Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine)Related Search:

TRANS-4-(TRIFLUOROMETHYL)CYCLOHEXANAMINE trans-1,2-Bis(methylamino)cyclohexane, (R,R)-(-)-N,Nμ-Dimethyl-1,2-diaminocyclohexane (1R,2R)-(+)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL) (1R,2R)-(+)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2-DIPHENYLPHOSPHINO-1-NAPHTHOYL) N,N'-Dimethyl-1,2-cyclohexanediamine

Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine 1,2-Cyclohexylenedinitrilotetraacetic acid (1S)-trans-1,2-Bis(methylamino)cyclohexane, (S,S)-N,Nμ-Dimethyl-1,2-diaminocyclohexane (+/-)-TRANS-1,2-BIS(2-MERCAPTOACETAMIDO)CYCLOHEXANE TRANS-1,2-DIAMINOCYCLOHEXANE-N,N,N',N'-TETRAACETIC ACID MONOHYDRATE

(-)-N,N'-(1R,2R)-1,2-DIAMINOCYCLOHEXANEDIYLBIS(2-PYRIDINECARBOXAMIDE) (+/-)-TRANS-1,2-BIS(THIOACETATEACETAMIDO)CYCLOHEXANE (+)-U-50488 HYDROCHLORIDE (+/-)-TRANS-1,2-BIS(CHLOROACETAMIDO)CYCLOHEXANE (1R,2R)-N,N,N''N''-TETRAMETHYL-1,2-CYCLOHEXANEDIAMINE

(+/-)-(5ALPHA,7ALPHA,8BETA)-3,4-DICHLORO-N-METHYL-N-(7-[1-PYRROLIDINYL]-1-OXASPIRO[4.5]DEC-8-YL)BENZENEACETAMIDE MESYLATE trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride (4AR,8AR)-DECAHYDRO-QUINOXALINE

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trans-(1R,2R)-N,N'-BisMethyl-1,2-cyclohexanedia 1,2-CyclohexanediaMine,N1,N2-diMethyl-, (1R,2R)-rel- trans-N,N'-DiMethylcyclohexane-1,2-diaMin rel-(1R,2R)-N1,N2-DiMethylcyclohexane-1,2-diaMine (1R,2R)-rel-N1,N2-DiMethylcyclohexane-1,2-diaMine trans-N,N'-Dimethyl-1,2-cyclohexanediamine,98% TRANS-N,N''-DIMETHYL-1,2-CYCLOHEXANEDIAMINE (1R,2R)-rel-N1,N2-Dimethyl-1,2-cyclohexanediamine (+/-)-trans-1,2-Diamino-N,N'-dimethylcyclohexane rel-(1R,2R)-1-N,2-N-diMethylcyclohexane-1,2-diaMine Trans-(1R,2R)-N,N'-bisMehtyl-1,2-cyclohexanediaMine (1R,2R)-rel-N1,N2-Dimethyl-1,2-cyclohexanediamine (Oxaliplatin) (1R,2R)-rel-N1,N2-Dimethyl-1,2-cycloh trans-1,2-Bis(methylamino)cyclohexane (Oxaliplatin) TRANS-N,N'-DIMETHYLCYCLOHEXANE trans-N,N'-Bismethyl-1,2-cyclohexanediamine N,N'-Dimethyl-trans-1,2-cyclohexanediamine trans-N,N'-Dimethylcyclohexane-1,2-diamine> trans-N,N'-DimethyL 1,2-Cyclohexanediamine, N,N'-dimethyl-, (1R,2R)-rel- rans-N,N'-dimethylcyclohexane-1,2-diamine Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine ISO 9001：2015 REACH C8H18N2 TRANS-1,2-BIS(METHYLAMINO)CYCLOHEXANE 67579-81-1 trans-N,N TRANS-1,2-BIS(METHYLAMINO)CYCLOHEXANE TRANS-N,N'-DIMETHYLCYCLOHEXANE-1,2-DIAMINE (1R,2R)-N1,N2-dimethylcyclohexane-1,2-diamine t-DMACH trans-N1,N2-DiMethylcyclohexane-1,2-diaMine Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine trans-N,N'-Dimethyl-1,2-cyclohexanediamine trans-N,N'-Dimethylcyclohexane-1,2-diamine 67579-81-1 C6H10NHCH32 Chiral Nitrogen DACH&Trost Series Chiral Reagents Miscellaneous Reagents