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4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE

4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Structure
CAS No.
191219-80-4
Chemical Name:
4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE
Synonyms
YM 976;4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE;4-(3-Chloro-phenyl)-1,7-diethyl-1H-pyrido[2,3-d]pyrimidin-2-one;Pyrido[2,3-d]pyrimidin-2(1H)-one, 4-(3-chlorophenyl)-1,7-diethyl-;YM-976,Phosphodiesterase (PDE),PDE4 inhibitor,inhibit,phosphodiesterase 4,anti-inflammatory activities,antigen-induced airway responses,Inhibitor,YM976,YM 976
CBNumber:
CB5725034
Molecular Formula:
C17H16ClN3O
Molecular Weight:
313.78
MOL File:
191219-80-4.mol
Modify Date:
2023/5/18 11:31:12
Request For Quotation

4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Properties

Melting point 132.7-134.0 °C(lit.)
Boiling point 485.4±55.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO: 16 mg/mL
form solid
pka 2.11±0.20(Predicted)
color pale yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3

4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Chemical Properties,Uses,Production

Uses

YM 976 is an inhibitor of PDE4.

Biological Activity

Orally active PDE4 inhibitor (IC 50 = 2.2 nM). Low emetogenic activity, suggested to be due to poor brain penetration.

4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Suppliers

Global( 42)Suppliers
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Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
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Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 China 4428 55 Inquiry
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Supplier Advantage
Nantong HI-FUTURE Biology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Riedel-de Haen AG 87
BIOTREND Chemicals AG 62
Tocris Bioscience 77
ApexBio Technology 58
Guangzhou Isun Pharmaceutical Co., Ltd 55
Shanghai Haoyang Biological Technology Co., Ltd. 58
Shanghai Yuda Industrial Co., Ltd. 58

191219-80-4(4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE)Related Search:

2-AMINO-3-ETHYL-6-METHYLPYRIDINE 2,5-DIMETHYL-PYRIDINEFORMAMIDE 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE
YM 976 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE 4-(3-Chloro-phenyl)-1,7-diethyl-1H-pyrido[2,3-d]pyrimidin-2-one Pyrido[2,3-d]pyrimidin-2(1H)-one, 4-(3-chlorophenyl)-1,7-diethyl- YM-976,Phosphodiesterase (PDE),PDE4 inhibitor,inhibit,phosphodiesterase 4,anti-inflammatory activities,antigen-induced airway responses,Inhibitor,YM976,YM 976 191219-80-4 C17H16N3OCl Cell Signaling and Neuroscience Cell Biology BioChemical Phosphodiesterase Inhibitors Cyclic Nucleotide Metabolism G Proteins and Cyclic Nucleotides Cyclic Nucleotide related