Chinese english Japanese Germany Korea

ITE

ITE Structure
CAS No.
448906-42-1
Chemical Name:
ITE
Synonyms
ITE;ARYL HYDROCARBON RECEPTOR LIGAND;ITE,Aryl Hydrocarbon Receptor,Inhibitor,inhibit,AhR;Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate;2-(1'H-INDOLE-3'-CARBONYL)-THIAZOLE-4-CARBOXYLIC ACID;methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate;2-(1H-INDOL-3-YLCARBONYL)-4-THIAZOLECARBOXYLIC ACID METHYL ESTER;2-(1'H-indole-37-carbonyl)-thiasole-4-carboxylic acid methyl ester;4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester
CBNumber:
CB5754713
Molecular Formula:
C14H10N2O3S
Molecular Weight:
286.31
MOL File:
448906-42-1.mol
Modify Date:
2023/6/30 15:45:59
Request For Quotation

ITE Properties

Melting point 234 - 236°C
Boiling point 520.4±48.0 °C(Predicted)
Density 1.427±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 30 mg/mL, soluble
pka 14.38±0.30(Predicted)
form solid
color Off-White to Light Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

ITE Chemical Properties,Uses,Production

Uses

ITE is an endogenous AHR ligand that parenterally or orally induces FoxP3+ Treg that suppress exprimental autoimmune encephalomyelitis. ITE promotes the induction of active immunology tolerance and identifies nontoxic endogenous AHR ligands.

Biological Activity

Endogenous agonist for the transcription factor aryl hydrocarbon receptor (AHR); K i = 3 nM for binding to murine AHR. Transactivates DRE-containing reporter gene constructs in Hepa1c1c7 cells ~ 5-fold more potently than β -naphthoflavone. Active in vivo .

ITE Preparation Products And Raw materials

Raw materials

Preparation Products

ITE Suppliers

Global( 94)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
Zhejiang J&C Biological Technology Co.,Limited 58
Labnetwork lnc. 58
Alfa Chemistry 58
LEAP CHEM CO., LTD. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58

ITE Spectrum

ITE(448906-42-1)1HNMR

448906-42-1(ITE)Related Search:

4-Thiazolecarboxylic acid 2-acetylthiazole-4-carboxylic acid ITE 2-ACETYL-4-METHYLTHIAZOLE, 97%
ITE 2-(1H-INDOL-3-YLCARBONYL)-4-THIAZOLECARBOXYLIC ACID METHYL ESTER 2-(1'H-INDOLE-3'-CARBONYL)-THIAZOLE-4-CARBOXYLIC ACID 2-(1'H-indole-37-carbonyl)-thiasole-4-carboxylic acid methyl ester Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate ARYL HYDROCARBON RECEPTOR LIGAND 4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester ITE,Aryl Hydrocarbon Receptor,Inhibitor,inhibit,AhR 448906-42-1 C14H10N2O3S