ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Urine (urea) pyrimidine >2-Thiouracil
2-Thiouracil
- CAS No.
- 141-90-2
- Chemical Name:
- 2-Thiouracil
- Synonyms
- TU;2-thioxo-2,3-dihydropyriMidin-4(1H)-one;Thiouracil;2-TU;Nobilen;DERACIL;Thiouraci;tiouracyl;THIURACIL;NSC 19473
- CBNumber:
- CB5769908
- Molecular Formula:
- C4H4N2OS
- Molecular Weight:
- 128.15
- MOL File:
- 141-90-2.mol
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | >300 °C (lit.) |
|---|---|
| Density | 1.368 (estimate) |
| refractive index | 1.7000 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | 7.9g/l |
| pka | pKa 7.46 (Uncertain) |
| form | Fine Crystalline Powder |
| color | White to cream |
| Water Solubility | 0.5 g/L |
| λmax | 271nm(H2O)(lit.) |
| Merck | 14,9366 |
| BRN | 112227 |
| InChIKey | ZEMGGZBWXRYJHK-UHFFFAOYSA-N |
| CAS DataBase Reference | 141-90-2(CAS DataBase Reference) |
| IARC | 2B (Vol. Sup 7, 79) 2001 |
| NIST Chemistry Reference | 2-Thiouracil(141-90-2) |
| EPA Substance Registry System | Thiouracil (141-90-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H351 | |||||||||
| Precautionary statements | P281 | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 40-45-20/21/22 | |||||||||
| Safety Statements | 36/37-53-45 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YR1575000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29335995 | |||||||||
| NFPA 704 |
|
2-Thiouracil price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T7750 | 2-Thiouracil ≥99% | 141-90-2 | 25G | ₹2386.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7750 | 2-Thiouracil ≥99% | 141-90-2 | 100G | ₹6371.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7750 | 2-Thiouracil ≥99% | 141-90-2 | 250G | ₹13986 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7750 | 2-Thiouracil ≥99% | 141-90-2 | 1KG | ₹37995.3 | 2022-06-14 | Buy |
| ALFA India | ALF-A18119-22 | 2-Thiouracil, 98% | 141-90-2 | 100g | ₹2332 | 2022-05-26 | Buy |
2-Thiouracil Chemical Properties,Uses,Production
Chemical Properties
white to cream fine crystalline powder
Uses
2-Thiouracil has been used in the synthesis and characterization of silver colloid and film substrates and their applications in surface-enhanced Raman scattering (SERS)
Definition
ChEBI: A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.
Safety Profile
Moderately toxic by ingestion. Human teratogenic effects by unspecified routes: developmental abnormalities of the central nervous system, craniofacial area, and endocrine system. Human reproductive effects by unspecified route: effects on newborn, including viabllity index changes. Experimental teratogenic effects. Other experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. Used in the treatment of hyperthyroidism, angina pectoris, and congestive heart failure. See also MERCAPTANS and KETONES.
Purification Methods
Crystallise 2-thiouracil from water or EtOH. [Beilstein 24 H 323, 24 I 315, 24 II 171, 24 III/IV 1237.]
2-Thiouracil Preparation Products And Raw materials
Raw materials
Preparation Products
PYRIMIDIN-4-OL
4-CHLORO-N-METHYLPYRIMIDIN-2-AMINE
N-(4-AMINOPYRIMIDIN-2-YL)-N-METHYLAMINE
5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
4-Bromopyrimidine
4-THIOURACIL
4-Hydroxypyrimidine
4-Pyrimidinol
BENZYL-(2-METHYLSULFANYL-PYRIMIDIN-4-YL)-AMINE
4-Chloro-2-(methylsulfonyl)pyrimidine
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Global( 548)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JLS Laboratories Pvt Limited | +91 8790545679 | Hyderabad, India | 62 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| JLS Laboratories Pvt Limited | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Central Drug House(P) Ltd. | 58 |
| LOBA CHEMIE PVT.LTD. | 58 |
| Triveni chemicals | 58 |
| SynZeal Research Pvt Ltd | 58 |
| Scientific OEM | 38 |
| ALPHA CHEMIKA | 43 |
| Otto Chemie Pvt. Ltd. | 58 |
| A.J Chemicals | 58 |
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2-Mercapto-4-pyrimidone
2-THIOURACIL
2,3-dihydro-2-thioxo-4(1h)-pyrimidinone
DERACIL
2,3-dihydro-2-thioxo-4(1h)-pyrimidinon
Thiourea pyriMidine
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2-thioxo-2,3-dihydropyriMidin-4(1H)-one
2-mercapto-4(1h)-pyrimidinone
2-mercapto-4-pyrimidino
2-Mercapto-4-pyrimidinol
2-Mercaptopyrimid-4-one
2-Sulfanyl-4-pyrimidinol
2-Thio-1,3-pyrimidin-4-one
2-thio-2,4-(1h,3h)-pyrimidinedione
2-thio-4-oxo-1,3-pyrimidine
2-thio-4-oxypyrimidine
2-thio-6-oxypyrimidine
Uracil, 2-thio-
4-HYDROXY-2-MERCAPTOPYRIMIDINE / 2-THIOURACIL
2-THIO-URACYLE
THIURACIL
2-THIOURACIL VETRANAL, 250 MG
2-ThiouracilForSynthesis
2-Thiouracil, 98+%
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